Analgesic effect of nefopam on enhanced recovery after minimally invasive spine surgery: a randomized prospective study

Phase 3

Completed

• Conditions: Patients undergoing minimally invasive spine surgery; nefopam, minimally invasive spine surgery, enhanced recovery after surgery, postoperative pain

• Registration Number: TCTR20190525001
• Lead Sponsor: none

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-05-25
• Study Completion: 2020-09-25
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Patients undergoing minimally invasive spine surgery (MIS)
ASA physical status I-III

Exclusion Criteria

- Allergy to medications used in protocol
- History of seizure, MI, glaucoma
- Concurrent use MAO inhibitors
- Liver cirrhosis or end-stage renal disease (ESRD)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Morphine consumption 24 hours mg

Secondary Outcome Measures

Name	Time	Method
Time to first ambulation since operation complete hours,Hospital stay since operation complete days,Duration of tubing (drain and Foley) removal since operation complete hours,Postoperative pain score until day 3 Numerical rating scale 0-10,Incidence of neuropathic pain 24 hours Neuropathic pain questionnaire