The analgesic effect of Nefopam on enhanced recovery after spinal surgery: a randomized clinical trial

Phase 4

• Conditions: degenerative lumbar/sacral spine diseasedegenerative lumbar/sacral disc diseaselumbar/sacral scoliosisherniated lumbar/sacral disc; nefopam; degenerative lumbar spine; postoperative pain; spine surgery; enhanced recovery after surgery

• Registration Number: TCTR20190615001
• Lead Sponsor: none

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-06-15
• Study Completion: 2021-04-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Enrolling by invitation
• Sex: All
• Target Recruitment: 74

Inclusion Criteria

patients who undergo lumbar/sacral spine surgery
ASA physical status 1-3

Exclusion Criteria

History of drug allergy (which is used in this study)
History of epilepsy, coronary heart disease, glaucoma
current use of MAO inhibitors drug
liver cirrhosis or end stage renal failure
tumor of infection around the surgical site
history of spine surgery in previous 12 months

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Opioid consumption in first 24 hours after surgery 24 hours after surgery mg

Secondary Outcome Measures

Name	Time	Method
Pain recovery room, post-operative day 1-3 VAS,ambulation after surgery time to first sit, time to first walk, length of stay,complication after surgery from analgesic drugs and surgery