Post-ICU Neurocognitive Performance and Sleep Quality Ratings Following Exposure to a Medical ICU Sleep Quality Improvement Project
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Neurobehavioral Manifestations
- Sponsor
- Johns Hopkins University
- Enrollment
- 88
- Locations
- 1
- Primary Endpoint
- Digit span test score
- Status
- Completed
- Last Updated
- 14 years ago
Overview
Brief Summary
The purpose of this study is to understand patients' neurocognitive performance shortly after discharge from the Medical Intensive Care Unit (MICU) and the potential effect of sleep quality in the MICU on those neurocognitive outcomes. The investigators hypothesize that post-ICU neurocognitive function and patient overall ICU sleep experience will improve through a pre-existing MICU sleep improvement initiative.
Detailed Description
Despite decades of scientific interest in evaluating sleep among critically ill patients, little is known about the effects of intensive care unit (ICU)-associated sleep disturbances on patient outcomes. Furthermore, few interventions have been rigorously evaluated to demonstrate efficacy in improving sleep in the ICU and associated patient outcomes. Post-ICU neurocognitive test performance data from this study will be linked to a pre-existing Quality Improvement (QI) project for patient sleep in the MICU. We hypothesize that patients' post-ICU neurocognitive performance (delirium status, attention, short-term memory, processing speed, and executive function) will positively correlate with scores from a previously-published Sleep in the Intensive Care Unit Questionnaire. In addition, we hypothesize that both neurocognitive performance and the Sleep in the Intensive Care Unit Questionnaire will improve during the multi-stage MICU-wide sleep QI project. Our project will provide valuable empirical evidence to help support guidelines for promoting sleep in the ICU setting.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\>=18 years old
- •Spent at least one full night (i.e. 7pm to 7am) in the Johns Hopkins Hospital (JHH) Medical Intensive Care Unit (MICU).
- •Discharged directly from MICU to an in-patient medical step-down or ward bed at JHH.
Exclusion Criteria
- •Previously enrolled in the study (i.e. repeat discharge from MICU)
- •Pre-existing cognitive impairment, including hepatic encephalopathy, long-term alcohol abuse, and neurological disease (e.g., dementia, prior stroke, cerebral palsy, traumatic brain injury, active seizures)
- •Unable to speak and/or understand English
- •\> 96 hours between MICU discharge and testing
- •Visual or hearing impairment, inability to read, or inability to use a writing instrument preventing administration of the neurocognitive tests
- •Spent at least one night in an ICU other than JHH MICU during current hospitalization
Outcomes
Primary Outcomes
Digit span test score
Time Frame: within 96 hours of Intensive Care Unit (ICU) discharge
Secondary Outcomes
- Sleep in the ICU Questionnaire(within 96 hours of ICU discharge)
- Trail Making Test (Part A + B) times(within 96 hours of ICU discharge)
- Delirium status(within 96 hours of ICU discharge)