Comparing the effects of ozone water vs regular water on gum health after cleaning in gum disease.

Not yet recruiting

Conditions: Chronic periodontitis,

Registration Number: CTRI/2025/03/083548

Lead Sponsor: Dr Abha Chavan

Brief Summary: Periodontitis is a long-term gum disease that affects the tissues supporting your teeth, like the gums, ligaments, and bone. It starts with minor bone loss and can worsen over time, leading to serious damage. There are different stages of periodontitis, and Stage II and III are marked by moderate bone loss and signs like deep pockets between your teeth and gums, along with bleeding when you probe the gums.

One way to treat this condition is by flushing out the harmful bacteria in the pockets between the gums and teeth.

Ozone, a form of oxygen with extra energy, has been studied as a possible alternative. It’s thought to be more powerful because it kills bacteria, reduces inflammation, and helps tissues heal faster. Ozone could be especially useful in treating the bacteria that cause periodontitis, like *Porphyromonas gingivalis* and *Tannerella forsythia*.

This study is comparing the effectiveness of ozonized water (water with ozone in it) and regular water in treating Stage II and III periodontitis. By looking at things like how much the pockets between the teeth shrink and how much attachment the gums have to the teeth, the study wants to see if ozonized water leads to better results in treating the disease.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 58

Inclusion Criteria

Age between 18 to 60 years of age Systemically healthy patients Subjects with minimum 20 natural teeth remaining Subjects having Stage II and III Periodontitis.

Exclusion Criteria

Patients with systemic disease Patients consuming any form of tobacco Pregnant and Lactating women Having symptoms of acute illness during time of study.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pocket Probing Depth, Clinical Attachment Loss, Cumulative Periodontal Sum Score, C Reactive Protein.	1 month

Secondary Outcome Measures

Name	Time	Method
Plaque Index, Modified Sulcular Bleeding Index.	Baseline & 1 month

Trial Locations

Locations (1): K.M Shah Dental College and Hospital , Sumandeep Vidyapeeth.
🇮🇳
Vadodara, GUJARAT, India
K.M Shah Dental College and Hospital , Sumandeep Vidyapeeth.
🇮🇳Vadodara, GUJARAT, India
Dr Abha Satyendranath Chavan
Principal investigator
8180032045
drabhasatyendra30@gmail.com