CTRI/2018/02/011987
Completed
未知
Frequency of Circulating Tumor Cells (CTCs) and Amount of Cell-free DNA (cfDNA) in Cirrhotic Patients With Hepatocellular Carcinoma (HCC): A case control study
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Health Condition 1: null- HepatoCellular CarcinomaHealth Condition 2: K746- Other and unspecified cirrhosis ofliver
- Sponsor
- Institute of liver and Biliary Sciences
- Enrollment
- 53
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\) Age between 18\-70 years.
- •2\) Proven cirrhosis (Defined in appendix 1\).
- •3\) HCC proven by standard radiological criteria within last 1\-month
- •4\) No HCC on dynamic CT and/or dynamic MRI (protocol defined in appendix 1\) done within last 1 month
Exclusion Criteria
- •1\) Previous biopsy or FNA of the tumor.1
- •2\) Previous invasive radiological procedures TACE/RFA.
- •3\) Previous or ongoing chemotherapy or biological therapy.
- •4\) Previous liver resection or transplant.
- •5\) Segmental / main PV thrombosis.2
- •6\) Atypical enhancement on imaging
- •7\) Extrahepatic metastatic spread of HCC3
- •8\) Coexisting sepsis.
- •9\) Renal dysfunction, as defined by serum creatinine \>1\.5mg/dL.5
Outcomes
Primary Outcomes
Not specified
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