MedPath

Comparisson of the Efficacy of Ringer's Lactate Serum as a Base Solution in Modified Del Nido Cardioplegia with Standard Del Nido Cardioplegia on the Outcomes in Patients Undergoing Coronary Artery Bypass Graft

Not Applicable
Recruiting
Conditions
Coronary artery bypass graft.
Mechanical complication of coronary artery bypass graft and biological heart valve graft
T82.2
Registration Number
IRCT20210825052284N1
Lead Sponsor
Shahid Beheshti University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
60
Inclusion Criteria

Candidate patients for coronary artery bypass graft
Candidate patients for 3 to 4 vascular grafts
Age between 18 and 75 years
Written informed consent to participate in the study
An ejection fraction higher than 35% before surgery
Lack of multi-organ failure before surgery

Exclusion Criteria

Re-operation
Proven infection or inflammation within the last month

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Ejection fraction. Timepoint: Before surgery, after surgery, and 24 hours after admission to the intensive care unit. Method of measurement: Echocardiography.;Duration of mechanical ventilation. Timepoint: Daily after surgery. Method of measurement: Medical record of the patients.;Arrhythmia incidence. Timepoint: Daily after surgery. Method of measurement: Electrocardiogram device and cardiologist's interpretation.;Inotrope administration. Timepoint: Daily after surgery. Method of measurement: Medical record of the patients.
Secondary Outcome Measures
NameTimeMethod
Troponin level. Timepoint: Before surgery, after surgery, and 24 hours after admission to the intensive care unit. Method of measurement: Laboratory report.;Lactate dehydrogenase level. Timepoint: Before surgery, after surgery, and 24 hours after admission to the intensive care unit. Method of measurement: Laboratory report.
© Copyright 2025. All Rights Reserved by MedPath