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Modafinil in der Behandlung von Müdigkeit bei Tumorpatienten - eine randomisierte doppelblinde N=1 Studie - Modafinil for treatment of fatigue in cancer patients

Phase 1
Conditions
advanced cancer disease
Registration Number
EUCTR2005-002699-13-DE
Lead Sponsor
Department of Palliative Medicine, RWTH Aachen
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
All
Target Recruitment
20
Inclusion Criteria

patients with advanced cancer
treated in the paliative care unit
palliative prognostic index <= 6 (indicating high probability of survival >= 3 weeks
severe fatigue on a 4-step categorical scale for self-assessment of the patient
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

nonmalignant disease
patients not able to complete self-assessment
palliative prognostic index >6
patient refuses to participate
pregnancy or lactation
impaired organ function from liver, renal or cardiac disease or hypertonus that does not allow treatment with modafinil in the opinion of the investigator
investigator finds burden for the patient to high

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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