The Effect of Inhalation Anesthesia and Total Intravenous Anesthesia on Systemic Inflammatory Immune Index in Major Abdominal Cancer Surgeries
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Systemic Immune Activation
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
- Enrollment
- 84
- Locations
- 1
- Primary Endpoint
- investigate the effect of anesthesia management on the change of preoperative systemic inflammatory immune index(SII) and postoperative 2.hour and 24.hour SII value
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
The effects of different anesthesia methods on the immune system are variable. In this study, we investigated the effect of inhalation anesthesia and total intravenous anesthesia on the SII value in major abdominal cancer surgeries.
Detailed Description
The study was planned prospectively, observationally, on a total of 90 patients who underwent major abdominal cancer surgery. 84 patients were evaluated. The patients were seperated in two groups as inhalation anesthesia and total intravenous anesthesia (TIVA). The demographic data of the patients, type of cancer, type of surgery performed, ASA classification, preoperative chemotherapy intake, preoperative hemogram, postoperative 2nd and 24th hour hemogram, intraoperative and postoperative blood transfusion, and duration of surgery were recorded. Platelet, neutrophil, lymphocyte and SII values were saved.
Investigators
Arsen Güngör
Anesthesiology and Reanimation Specialist
Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Eligibility Criteria
Inclusion Criteria
- •major abdominal cancer surgeries
Exclusion Criteria
- •blood transfusion in last 72 hours
- •patients with infection
- •hematologic malignancy
- •patient controlled analgesia
Outcomes
Primary Outcomes
investigate the effect of anesthesia management on the change of preoperative systemic inflammatory immune index(SII) and postoperative 2.hour and 24.hour SII value
Time Frame: preoperative SII noted, postoperative 2.hour noted and postoperative 24.hour noted
systemic inflammatory immune index calculated by (platelet x neutrophil)/lymphocyte