High Flow Nasal Cannula vs Noninvasive Ventilation in Patients With Hypoxic Respiratory Failure Following Blunt Chest Trauma, a Randomized Clinical Trial

Ain Shams University1 site in 1 country120 target enrollmentAugust 1, 2022

ConditionsBlunt Injury of Thorax

Overview

Phase: N/A
Intervention: Not specified
Conditions: Blunt Injury of Thorax
Sponsor: Ain Shams University
Enrollment: 120
Locations: 1
Primary Endpoint: PaO2/FiO2 ratio
Status: Completed
Last Updated: last year

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

to compare high flow nasal cannula against noninvasive ventilation in patients with non-sever blunt chest trauma in improvement of oxygenation, need for intubation and mechanical ventilation within 28 days

Registry

clinicaltrials.gov

Start Date

August 1, 2022

End Date

April 1, 2024

Last Updated

last year

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Ain Shams University

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Age ≥18 y,
•Willing and able to provide written informed consent prior to performing study procedures,
•currently hospitalized and requiring medical care for non-sever blunt chest trauma (abbreviated injury severity scale ≤ 2) SpO2 90% or less while breathing 10 L/min.

Exclusion Criteria

•Contraindications of noninvasive ventilation (face trauma or surgery, airway obstruction, upper gastrointestinal tract bleeding, disturbed level of consciousness), -smoker
•intubation for any cause other than respiratory cause