High Flow Nasal Cannula vs Noninvasive Ventilation in Patients With Hypoxic Respiratory Failure Following Blunt Chest Trauma
Not Applicable
Completed
- Conditions
- Blunt Injury of Thorax
- Interventions
- Device: high flow nasal cannulaDevice: noninvasive ventilation
- Registration Number
- NCT05527431
- Lead Sponsor
- Ain Shams University
- Brief Summary
to compare high flow nasal cannula against noninvasive ventilation in patients with non-sever blunt chest trauma in improvement of oxygenation, need for intubation and mechanical ventilation within 28 days
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
- Age ≥18 y,
- Willing and able to provide written informed consent prior to performing study procedures,
- currently hospitalized and requiring medical care for non-sever blunt chest trauma (abbreviated injury severity scale ≤ 2) SpO2 90% or less while breathing 10 L/min.
Exclusion Criteria
- Contraindications of noninvasive ventilation (face trauma or surgery, airway obstruction, upper gastrointestinal tract bleeding, disturbed level of consciousness), -smoker
- intubation for any cause other than respiratory cause
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description high flow nasal cannula high flow nasal cannula - noninvasive mechanical ventilation noninvasive ventilation -
- Primary Outcome Measures
Name Time Method PaO2/FiO2 ratio 3 successive days mean value of three successive PaO2/FiO2 ratio in mmHg between both groups
- Secondary Outcome Measures
Name Time Method Discomfort score 3 successive days Discomfort related to oxygen delivery devices will be evaluated using a 10- point numeric scale which low number is low discomfort.
Trial Locations
- Locations (1)
Ain Shams University hospitals
🇪🇬Cairo, Egypt