Fear acquisition and extinction mechanisms in relation to treatment outcome: a study in patients with anxiety disorders - Fear acquisition & extinction mechanisms in relation to treatment outcome

niversiteit Utrecht0 个研究点目标入组 310 人开始时间: 待定最近更新: 2024年4月29日

适应症

试验速览

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•a. Patients with a lifetime diagnosis of the following disorders as a primary diagnosis: Panic disorder with or without agoraphobia, social anxiety disorder, specific phobia, generalized anxiety disorder, post-traumatic stress disorder and obsessive compulsive disorder.
•b. Males and females between 18 and 65 years old.
•c. Command of the Dutch language (i.e. ability to understand procedures and questionnaires).
•d. Normal or corrected normal vision.;The inclusion criteria for the healthy controls participating in conditioning task 1 are the same as described above, with the exception of criterium a.

•a. Current comorbid severe psychiatric disorder in the past 6 months: i.e. severe major depressive disorder (BDI * 30), bipolar disorder, psychotic disorder.
•b. Lifetime history of substance dependence, or substance abuse within the last three months.
•c. Mental retardation (IQ < 80)
•d. History of any physical disease which may confound the results of the study according to the investigator, like brain damage.
•e. Hearing/ vision problems
•f. Current use of antipsychotic medication;The inclusion criteria for the healthy controls participating in conditioning task 1 are the same as described above.

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