Effects of Walking Exercise on Brain-Derived Neurotrophic Factor, Cognition, Participation and Quality of Life among Stroke Survivors
- Conditions
- Nervous System Diseases
- Registration Number
- PACTR201903762696119
- Lead Sponsor
- Bayero Uiversity Kano
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 57
1.First incidence of ischaemic or haemorrhagic stroke with blood pressure under control
2.cognitive function score of 10 to 25 on the Montreal Cognitive Assessment (MoCA)
3.Adequate balance control of less than 30 seconds scores indicated by Timed Up-and-Go (TUG) test
4.Able to read and write in either English or Hausa language
5.Mild to moderate upper limb impairment with wrist, metacarpophalangeal and interphalangeal joint extension of more than 20 degrees and preserved ability to grasp
7.Able to complete self-paced 6 Minutes Walk (6MW) test at an intensity of perceived exertion of 12 to 13 on the Borg 6-20 Scale.
a)Individuals with severe cardiac problems as determined using physical activity readiness questionnaire and aerobic exercise testing. This group of participants may not be able to cope with the exercise intensity.
b)Individuals with severe depression as indicated by Physical Health Questionnaire (PHQ) score of more than 15 and stroke survivors with other conditions that may cause cognitive impairments such as Parkinson’s disease, Alzheimer’s disease or traumatic head injury etc.
c)Individuals with severe joint disorders such as osteoarthritis, rheumatoid arthritis that may become worse during exercise or can make performance of exercise difficult.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method