An Australian Regional Hospital's Oesophagectomy Outcomes
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- mortality
研究概览
简要总结
Literature review/rationale for project
- Oesophageal cancer is associated with a grim prognosis despite many advances in treatment. Oesophagectomy is a key component of the care of patients who are candidates for curative treatment, however it is associated with substantial morbidity.
- Several studies have suggested that oesophagectomies performed at higher volume tertiary centres are associated with lower morbidity and mortality than lower volume centres, and this has prompted changes to policy in countries such as Great Britain, Canada and the Netherlands with regards to the centralisation of these cases. A higher volume centre within Australia is likely to perform 6 or more procedures per year.
- Currently within Australia, centralisation on a large scale has not occurred. This has been limited in part by resource provision and geographical barriers. Therefore, oesophagectomies in Australia are still routinely performed in regional centres. However, there is a paucity of recent outcomes data from these centres.
Aims/objectives
- Retrospective review of oesophagectomies undertaken in a single regional centre in Tasmania, Australia over 10 years (January 2014 to December 2023)
- Assess outcomes (long and short-term complications and mortality) and compare to morbidity and mortality rates from larger international centres
详细描述
Research aims/objectives
- Retrospective review of oesophagectomies undertaken in a single regional centre in Tasmania, Australia over 10 years (January 2014 to December 2023)
- Assess outcomes (long and short-term complications, mortality, survival) and compare to published outcomes from larger national and international centres
Project Design Research project setting: Launceston General Hospital (Tasmania, Australia)
Methodological approach: Retrospective case series
Participants
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients who underwent oeophagectomy at Launceston General Hospital between January 2014 to December 2023
排除标准
- 未提供
结局指标
主要结局
mortality
时间窗: from date of surgery to end of study (November 2024) for a timeframe up to 10 years
date of death from any cause or date of palliation whichever came first
Anastomotic leak
时间窗: from date of surgery to end of study period (Nov 2024), assessed up to 10 years
Grade 1-3, diagnosed radiologicaly, requiring intervention (surgical or non-surgical)
Length of stay
时间窗: from date of surgery to discharge date of hospital admission, approximately 2-4 weeks in most cases but assessed up to 12 weeks
total inpatient hospital stay and total ICU length stay
次要结局
未报告次要终点
研究者
Renishka Sellayah
Principal investigator
Launceston General Hospital
