Oral Manifestations of Human Immunodeficiency Virus Infection in High Risk Groups
Completed
- Conditions
- HIV InfectionsCandidiasis, Oral
- Registration Number
- NCT00004781
- Lead Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
- Brief Summary
OBJECTIVES: I. Evaluate the development of oral manifestations of human immunodeficiency virus infection in relationship to the onset of immunologic alterations and systemic symptoms in different risk groups: gay/bisexual men, male intravenous drug users, and female intravenous drug users.
II. Evaluate the immune and inflammatory response to periodontal and other microbial pathogens.
III. Evaluate the bacterial species infecting the oral cavity in patients in these risk groups.
- Detailed Description
PROTOCOL OUTLINE:
Patients undergo a periodontal assessment every 6 months until medically unable to continue. The oral/dental exam includes saliva and gingival crevicular fluid analysis and, as indicated, oral photographs.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 250
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method