Trial of human immunodeficiency virus (HIV) screening in Primary Care
Not Applicable
Completed
- Conditions
- Human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS)Infections and InfestationsUnspecified human immunodeficiency virus [HIV] disease
- Registration Number
- ISRCTN63473710
- Lead Sponsor
- Queen Mary's University of London (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 23000
Inclusion Criteria
1. Individuals aged 16 years or older registering at study practices, either sex
2. Individuals able to undertake the pre-test discussion in English or with a suitable translator
Exclusion Criteria
1. Aged under 16 years
2. Individuals with limited English abilities, who are unable to understand the info sheet or, who are unable to engage with the pre-test discussion for HIV testing
3. Known HIV positive patients
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Rates of new HIV diagnoses: numbers of rapid and standard HIV tests done in new patient health checks<br><br>Outcomes are measured quarterly.
- Secondary Outcome Measures
Name Time Method Immunological outcomes:<br>1. Numbers of patients diagnosed during early HIV infection defined as CD4 count higher than 200 cells per cubic millimetre blood<br><br>Viral outcomes:<br>2. HIV viral load, clade and genotype of the virus at the time of diagnosis as predictors of disease progression<br><br>Health service use:<br>3. Numbers of registering patients<br>4. Numbers of standard HIV tests done opportunistically<br>5. Numbers of New Patient Health Checks carried out<br><br>Economic outcomes:<br>6. Cost-effectiveness of the intervention compared to standard of care<br><br>Outcomes are measured quarterly.