Efficacy of Ibuprofen gargle for oral lichen planus: A comparison study.

Phase 2

Recruiting

• Conditions: oral lichen planus; D017676

• Registration Number: JPRN-jRCTs051220009
• Lead Sponsor: Kakei Yasumasa

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-04-22
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

(1) Patients with oral lichen planus or oral lichen planus-like lesions.
(2) Patients with pain in the oral cavity averaging 20 mm or more on the Visual Analog Scale (VAS) over the past 7 days from the date of registration.
(3) Patients who are receiving treatment (both systemic and local) for the lesion and have been using the drug at a certain dose for at least 28 days prior to the date of registration.
(4) Patients aged 20 years or older at the time of a cquisition consent.
(5) Patients for whom documented consent has been obtained regarding their voluntary participation in this clinical study.

Exclusion Criteria

(1) Patients who have peptic ulcer.
(2) Patients with concurrent severe or uncontrolled concomitant medical conditions.
(3) Patients with history of hypersensitivity to any component of ibuprofen gargle.
(4) Patients who impaired cardiac function or clinically significant heart disease.
(5) Patients with aspirin-induced asthma.
(6) Patients who use analgesic drug at least once a week for any chronic pain.
(7) Patients with dementia, psychiatric symptoms, drug addiction and alcoholism.
(8) Pregnant or lactating women.
(9) Patients that the investigator deems inappropriate.

Study & Design

• Study Type: Interventional
• Study Design: Not specified