Functional outcome in two different designs of knee replacements

Completed

• Conditions: Total knee replacement surgery; Musculoskeletal Diseases; Gonarthrosis [arthrosis of knee]

• Registration Number: ISRCTN05635855
• Lead Sponsor: Queen Margaret University (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2008-07-24
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

Ninety suitable men and women (no age limits) with osteoarthritis undergoing a Total Knee Replacement (TKR) at the New Royal Infirmary, Edinburgh who are able to actively flex the knee more than 90 degrees will be recruited from the waiting list of three orthopaedic surgeons. Suitable patients will be identified from medical records and will be living in the Lothian region. All subjects will be medically fit for testing and have no other lower limb impairments.

Exclusion Criteria

1. Inflammatory polyarthritis
2. Disorders of the feet, ankles or hips or spine causing abnormal gait or significant pain
3. Dementia
4. Severe visual impairment
5. Neurological conditions affecting movement
6. Inability to give informed consent
7. Any other disorders of the contra-lateral knee causing abnormal gait or significant pain. Subjects with radiological evidence of osteoarthritis of the contra-lateral knee will be included provided the patient does not report significant pain or restriction in motion of the contra-lateral knee. Similarly patients with total knee arthroplasty of the contra-lateral knee will be included provided the patient does not report significant pain or restriction in motion of the contra-lateral knee.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Knee excursion during functional activities as measured using electrogoniometry. Primary and secondary outcome measures are collected around one to three weeks before surgery and one year after surgery for both groups.

Secondary Outcome Measures

Name	Time	Method
1. The passive range of motion of the knee<br>2. Flexor and extensor strength as measured using a MIE myometer<br>3. Function as measured by the American Knee Society Score<br>4. Function, stiffness and pain as measured by the Western Ontario and McMaster Universities (WOMAC) questionnaire<br>5. Quality of life, using the 36-item short form health survey, version 2 (SF-36 v2)<br>6. Pain, using the Visual Analogue Score (0 = no pain to 10 = unbearable pain)<br>7. Walking speed<br>8. Physical mobility as measured by an activity monitor (activPAL)<br>9. Canadian Occupational Performance Measure<br><br>Primary and secondary outcome measures are collected around one to three weeks before surgery and one year after surgery for both groups.