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Clinical Trials/NCT05993130
NCT05993130
Completed
Not Applicable

Kayseri City (Education and Research) Hospital

Kayseri Education and Research Hospital1 site in 1 country55 target enrollmentJanuary 15, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Severity of Osteoprosis
Sponsor
Kayseri Education and Research Hospital
Enrollment
55
Locations
1
Primary Endpoint
Does the severity of osteoporosis increase in patients with Covid-19 infection?
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

Osteoporosis is a condition characterized by decreased bone strength and an increased risk of fracture. Age, gender, body mass index, fragility fracture history, corticosteroid use, immobilization, smoking and alcohol use, endocrine pathologies besides inflammatory and infectious pathologies can also be effective in the development of osteoporosis. The aim of the study is to evaluate the effect of Covid-19 infection on the development of osteoporosis.

In this study, bone mineral density (BMD) measurements of patients with Covid-19 infection were examined. For this, dual-energy x-ray absorptiometry (DEXA) measurement was used. A total of 55 patients were included in the study and data such as age, height, weight, comorbidities, drugs used, and treatment methods were recorded. Results showed that the time spent in the intensive care unit was associated with the femoral neck T score in DEXA measurements of patients with Covid-19 infection. The use of drugs such as alendronate, zolendronate, denosumab or teriparatide during the treatment process did not have a statistically significant effect on the lumbar and femur T scores.

Registry
clinicaltrials.gov
Start Date
January 15, 2021
End Date
December 15, 2022
Last Updated
2 years ago
Study Type
Observational
Sex
Female

Investigators

Sponsor
Kayseri Education and Research Hospital
Responsible Party
Principal Investigator
Principal Investigator

Dr. Ayşe Güç

physical medicine and rehabilitation

Kayseri Education and Research Hospital

Eligibility Criteria

Inclusion Criteria

  • Female patients over the age of 18 who had dexa measurements twice before and after covid, with at least one year between two dexa measurements, and at least one month after covid infection were included in the study.

Exclusion Criteria

  • Under the age of 18, male patients, patients with a diagnosis other than Covid-19 infection that will affect bone metabolism between the two dexa shooting dates before and after covid, patients who use another drug other than covid treatment that will affect bone metabolism between the two dexa shooting dates before and after covid not included in the study

Outcomes

Primary Outcomes

Does the severity of osteoporosis increase in patients with Covid-19 infection?

Time Frame: 2020 August 2021 July

Study Sites (1)

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