Single Breath Hold Abdominal MRI

Not Applicable

Completed

• Conditions: Abdominal MRI
• Interventions: Device: Respiratory-triggered T1w DISCO LAVA

• Registration Number: NCT02434471
• Lead Sponsor: Duke University

Brief Summary

The purpose of this study is to evaluate a single breath hold abdominal MRI protocol and compare the image quality of respiratory triggered 3D T1-weighted images against conventional breath hold images.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2015-04-28
• Study First Submitted QC: 2015-04-30
• Study First Posted: 2015-05-05
• Study Start: 2016-01-12
• Primary Completion: 2017-06-01
• Study Completion: 2017-06-01
• Status Verified: 2018-05
• Results First Submitted: 2018-05-01
• Results First Submitted QC: 2018-05-01
• Results First Posted: 2018-05-31
• Last Update Submitted: 2018-05-31
• Last Update Posted: 2018-07-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 54

Inclusion Criteria

• undergoing abdominal MRI

Exclusion Criteria

• none

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Respiratory-triggered T1w DISCO LAVA	Respiratory-triggered T1w DISCO LAVA	The study will acquire extra image sets using DISCO LAVA with one breath hold during the arterial imaging phase. No additional breath holds will be required.

Primary Outcome Measures

Name	Time	Method
Noise Scores	During MRI, up to 60 minutes	Three investigators will independently evaluate MRI examinations. They will assign noise scores between respiratory triggered and corresponding breath hold acquisitions. 1 = no noise artifact; 2 = minimal noise artifact, no effect on diagnostic quality; 3 = moderate noise artifact with some, but not severe, effect on diagnostic quality; 4 = severe noise artifact, images degraded but interpretable; and 5 = severe noise artifact, images nondiagnostic.
Motion Artifact Scores	During MRI, up to 60 minutes	Three investigators will independently evaluate MRI examinations. They will assign motion scores between respiratory triggered and corresponding breath hold acquisitions. 1 = no motion artifact; 2 = minimal motion artifact, no effect on diagnostic quality; 3 = moderate motion artifact with some, but not severe, effect on diagnostic quality; 4 = severe motion artifact, images degraded but interpretable; and 5 = extensive motion artifact, images nondiagnostic.

Trial Locations

Locations (1)

DukeUMC; 🇺🇸 Durham, North Carolina, United States