ANIRVID: A multi-center study to evaluatethe effect of complimentary alternative interventions on perinatal depression and itsassociated heart and thyroid function using conventional techniques, metabolomicsand point of care device.

Perinatal depression is highly prevalent and isa major public health issue as it affects both the mother and the newborn. Inaddition, several study findings implicate depression as one of the causativefactors for cardiovascular disease and thyroid disorders. Therefore, earlydetection of depression is necessary for the benefit of both mother and child.The main goal of this proposed multi-center study is to develop a more rapid,hand-held, mobile-health point-of-care (POC) diagnostic device - ‘Anirvid’ formonitoring key biomarkers related to perinatal depression and its relateddisorders at low-cost than current existing systems. In addition, the efficacyof drugs-free complementary and alternative interventions on perinatal depressionand its associated cardiac and thyroid functions will also be studied using‘Sai Vibrionics’ and ‘Primordial Chanting.’ Therefore, the proposed study willfacilitate early diagnosis, prognosis and modification in the management ofperinatal depression for the benefit of pregnant women and mothers in thesociety.