跳至主要内容
临床试验/CTRI/2010/091/000459
CTRI/2010/091/000459进行中(未招募)不适用

Meaningful task specific training for evaluation of functional and neuroplastic changes in post Stroke patients

未提供1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2009年12月18日最近更新:

试验速览

阶段
不适用
状态
进行中(未招募)
入组人数
100
试验地点
1
主要终点
Fugl Meyer Assessment (FMA) Action Research Arm Test (ARA) Motor Activity Log (MAL) Wolf Motor Function Test (WMFT)

研究概览

简要总结

Stroke remains a leading cause of disability in many countries including India. It can cause deficits in a number of neurologic domains, most commonly in the motor system.Standard motor rehabilitation after hemiparetic stroke typically involves an eclectic mix of approaches. However no therapeutic method gives remarkable improvement for motor deficit, making motor rehabilitation for stroke a major challenge.Further there is no strong clinical & research evidence for these methods.Task-specific training which focuses on the practice of skilled motor performance is the critical link to facilitate neural reorganization and "rewiring" in the central nervous system (CNS)Numerous studies have been done on task specific training; however type of task and specific method of training which can lead to better functional and neuroplastic changes in stroke patients has not been established yet.Hence there is need to develop more specific training methods based on meaningful task which would lead to better functional and neuroplastic changes in Stroke patients.

研究设计

分配方式
Computer generated randomization
盲法
Participant and Outcome Assessor Blinded

入排标准

入选标准

  • Age: 18 to 60 year, both male & femaleHemiparesis (both right & left)unilateral stroke Normal one side visionAble to cope with intensive training program Medically stable Able to understand instructions 4 to 24 weeks after strokeModified Ashworth Scale.
  • 1,1+, 2, Brunnstrom Recovery Stage-Arm-2,3,4 & 5 Functional Ambulation Classificatio- I & above.

排除标准

  • Severe Aphasia (NIHSS*- 2 & 3)Cerebellar or thalamic infarctUncontrolled systemic or cardiovascular diseaseFixed contracturesShoulder subluxationCortical blindness (NIHSS.
  • 2 & 3)Multiple strokeAtaxiaSevere sensory loss (NIHSS -2)DementiaParticipation in any Pharmacological trialSevere depression*(National Institutes of Health Stroke Scale-NIHSS).

结局指标

主要结局

Fugl Meyer Assessment (FMA) Action Research Arm Test (ARA) Motor Activity Log (MAL) Wolf Motor Function Test (WMFT)

时间窗: Pre intervention, Post intervention, Follow up after 4 week

次要结局

  • Stroke Impact Scale (SIS)(Pre intervention, Post intervention, Follow up after 4 week)

研究者

发起方
未提供

研究点 (1)

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