Meaningful task specific training for evaluation of functional and neuroplastic changes in post Stroke patients
- Conditions
- Post Stroke subjects with hemiperesis
- Registration Number
- CTRI/2010/091/000459
- Brief Summary
Stroke remains a leading cause of disability in many countries including India. It can cause deficits in a number of neurologic domains, most commonly in the motor system.Standard motor rehabilitation after hemiparetic stroke typically involves an eclectic mix of approaches. However no therapeutic method gives remarkable improvement for motor deficit, making motor rehabilitation for stroke a major challenge.Further there is no strong clinical & research evidence for these methods.Task-specific training which focuses on the practice of skilled motor performance is the critical link to facilitate neural reorganization and "rewiring" in the central nervous system (CNS)Numerous studies have been done on task specific training; however type of task and specific method of training which can lead to better functional and neuroplastic changes in stroke patients has not been established yet.Hence there is need to develop more specific training methods based on meaningful task which would lead to better functional and neuroplastic changes in Stroke patients.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Closed to Recruitment of Participants
- Sex
- Not specified
- Target Recruitment
- 100
- Age: 18 to 60 year, both male & femaleHemiparesis (both right & left)unilateral stroke Normal one side visionAble to cope with intensive training program Medically stable Able to understand instructions 4 to 24 weeks after strokeModified Ashworth Scale.
- 1,1+, 2, Brunnstrom Recovery Stage-Arm-2,3,4 & 5 Functional Ambulation Classificatio- I & above.
- Severe Aphasia (NIHSS*- 2 & 3)Cerebellar or thalamic infarctUncontrolled systemic or cardiovascular diseaseFixed contracturesShoulder subluxationCortical blindness (NIHSS.
- 2 & 3)Multiple strokeAtaxiaSevere sensory loss (NIHSS -2)DementiaParticipation in any Pharmacological trialSevere depression*(National Institutes of Health Stroke Scale-NIHSS).
Study & Design
- Study Type
- Not specified
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Fugl Meyer Assessment (FMA) Action Research Arm Test (ARA) Motor Activity Log (MAL) Wolf Motor Function Test (WMFT) Pre intervention, Post intervention, Follow up after 4 week
- Secondary Outcome Measures
Name Time Method Stroke Impact Scale (SIS) Pre intervention, Post intervention, Follow up after 4 week
Trial Locations
- Locations (1)
Dept. of Neurology, CSMMU, Lucknow, UP, India.
🇮🇳Lucknow, UTTAR PRADESH, India
Dept. of Neurology, CSMMU, Lucknow, UP, India.🇮🇳Lucknow, UTTAR PRADESH, IndiaProf. Rajesh VermaPrincipal investigator08127442407kamalnarya@yahoo.com