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临床试验/NCT04672109
NCT04672109已完成不适用

The Effects of Different Montages of Transcranial Direct Current Stimulation on Muscle Strength in Healthy Adults

Mahidol University1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2020年11月16日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
80
试验地点
1
主要终点
Change from baseline muscle strength after tDCS

研究概览

简要总结

To investigate the effects of different montages of tDCS on muscle strength in healthy adults

详细描述

Electrode montage or placement of tDCS over primary motor cortex can be categorized into unilateral (anodal or cathodal electrode over primary motor area) and bilateral tDCS (both anodal and cathodal electrode over the cortex). Previous studies reported benefits of different tDCS montages on muscle performance in healthy participants. However, there is no guideline for tDCS montages. This study aims to investigate immediate effects of different tDCS montages on muscle strength in healthy participants.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Factorial
主要目的
Treatment
盲法
Triple (Participant, Investigator, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Healthy adults
  • •Age range between 18 - 60 years old
  • •Right-handed dominant identified by the Edinburg Handedness Inventory
  • •No recent muscle injuries of both limbs for a past 6-months

排除标准

  • •Consumed caffeine within 24 hours prior the experiment
  • •History of neurological symptoms i.e. seizures, weakness, loss of sensation or unclear history of pass illness
  • •Present of metal implantation, intracranial shunt, cochlear implantation or cardiac pacemakers
  • •Present of opened wound or infectious wound around scalp

研究组 & 干预措施

Anodal-tDCS

Experimental

Anodal transcranial direct current stimulation (tDCS) will be applied for 20 mins. Anode on the primary motor area (M1) of dominant hemisphere and Cathode on the supraorbital area of non-dominant hemisphere. Current intensity is fixed at 2 mA and current will flow continuously. The scope of intervention is to investigate effect of tDCS on muscle strength.

干预措施: Transcranial direct current stimulation (Device)

Cathodal-tDCS

Experimental

Cathodal transcranial direct current stimulation (tDCS) will be applied for 20 mins. Cathode on the primary motor area (M1) of non-dominant hemisphere and Anode on the supraorbital area of dominant hemisphere. Current intensity is fixed at 2 mA and current will flow continuously. The scope of intervention is to investigate effect of tDCS on muscle strength.

干预措施: Transcranial direct current stimulation (Device)

Dual-tDCS

Experimental

Dual transcranial direct current stimulation (tDCS) will be applied for 20 mins. Anode on the primary motor area (M1) of dominant hemisphere and Cathode on the primary motor area of non-dominant hemisphere. Current intensity is fixed at 2 mA and current will flow continuously. The scope of intervention is to investigate effect of tDCS on muscle strength.

干预措施: Transcranial direct current stimulation (Device)

Sham-tDCS

Sham Comparator

Dual transcranial direct current stimulation (tDCS) will be applied over C3-C4 or the motor area (M1) for 20 mins. Anode on dominant hemisphere, Cathode on non-dominant hemisphere. The scope of intervention is to investigate effect of tDCS on muscle strength.

干预措施: Transcranial direct current stimulation (Device)

结局指标

主要结局

Change from baseline muscle strength after tDCS

时间窗: Baseline (Pretest) and 40 minutes ( posttest)

Muscle strength will be measured in Newton by using a hand-held dynamometer.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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