Outcomes of Acute Kidney Injury in Critically Ill Patients

• Conditions: Acute Kidney Injury
• Interventions: Diagnostic Test: renal function test

• Registration Number: NCT03338127
• Lead Sponsor: Alaa H Fahmy

Brief Summary

this study to evaluate the frequency of acute kidney injury in critically ill patients in intensive care units.

Detailed Description

Acute kidney injury (AKI) affects approximately 20% of hospitalized patients and up to 67% of those admitted to an intensive care unit (ICU), making it among the most common organ dysfunctions among the critically ill . Depending on severity, Acute kidney injury (AKI) contributes to short-perimortality rates between 40% and 70% , and survivors are at increased risk for chronic kidney disease (CKD) and late death.

The diagnosis of Acute kidney injury (AKI) is only considered after achieving an adequate status of hydration and after excluding urinary obstruction; Acute kidney injury (AKI) is defined by the sudden decrease (in 48 h) of renal function, defined by an increase in absolute serum creatinine of at least (0.3 mg/dL) or by a percentage increase in serum creatinine ≥50% (1.5× baseline value), or by a decrease in the urinary output (documented oliguria \<0.5 mL/kg/h for more than 6hours).

The purpose of this study was to benchmark the outcomes of acute kidney injury in a critically ill surgical patients.We hypothesized that renal dysfunction in this population is common and is associated with a significantly higher burden of morbidity, mortality, and resource utilization

Study Timeline

• Status Verified: 2017-11
• Study First Submitted: 2017-11-01
• Study First Submitted QC: 2017-11-07
• Last Update Submitted: 2017-11-08
• Study First Posted: 2017-11-09
• Last Update Posted: 2017-11-13
• Study Start: 2017-12-01
• Primary Completion: 2018-06-30
• Study Completion: 2018-06-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• All patient with acute kidney injury in critical care units in Luxor international hospital

Exclusion Criteria

• Patients on chronic dialysis
• Previous acute kidney injury
• Nephrectomy
• Organ transplant
• Chronic kidney disease

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Participants	renal function test	all patients recruited in the trial will be investigated for renal function test

Primary Outcome Measures

Name	Time	Method
Acute kidney injury in critically ill patients	10 days	To evaluate the frequency of acute kidney injury in critically ill patients admitted in intensive care units.