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Clinical Trials/NCT03012308
NCT03012308
Unknown
Not Applicable

Evaluation of Left Ventricular Filling Pressures in Post-operative Cardiac Surgery: Trans-thoracic Ultrasound VS Invasive Pressure of the Left Atrium

University Hospital, Strasbourg, France1 site in 1 country100 target enrollmentDecember 20, 2016

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Myocardial Dysfunction
Sponsor
University Hospital, Strasbourg, France
Enrollment
100
Locations
1
Primary Endpoint
Compare the mean values of LAP between the group "high filling pressures" and the group "non-high filling pressures"
Last Updated
8 years ago

Overview

Brief Summary

As part of cardiac and hemodynamic evaluation of patients, echocardiographic measurements allow indirect evaluation of left ventricular filling pressures (LVFP). These ultrasound parameters, including mitral valve doppler and mitral ring doppler (in particular the E / E 'ratio), are well validated in medical cardiology and in some resuscitation patients. The measurement of filling pressures is an important daily element in the medical management of patients in intensive care, in particular on the hemodynamic and respiratory levels. No studies have evaluated the relevance of these markers in a postoperative context of cardiac surgery. Indeed, the surgery alters the cardiac function, which could modify the values of the echocardiographic parameters and their predictability. Left atrium pressure (LAP) directly reflects LVFP and is measured in cardiac surgical resuscitation by a surgically placed catheter as part of routine institutional care and will serve as gold-standard. To study the clinical significance of these LAP and LVFP values estimated by cardiac ultrasound, we will study their correlation with clinical and ultrasound signs of acute lung edema (ALE).

Registry
clinicaltrials.gov
Start Date
December 20, 2016
End Date
December 20, 2017
Last Updated
8 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
University Hospital, Strasbourg, France
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patient hospitalized in surgical resuscitation for cardiac surgery with heart-lung bypass machine

Exclusion Criteria

  • No consent
  • Mitral valve surgery
  • severe MI / severe mitral narrowing.
  • Absence of POG catheter
  • Urgent surgery
  • Heart transplant / mechanical assistance
  • Classics: minors, pregnant women, guardianship / curatorship / safeguarding,

Outcomes

Primary Outcomes

Compare the mean values of LAP between the group "high filling pressures" and the group "non-high filling pressures"

Time Frame: 6 postoperative hours of cardiac surgery of patients hospitalized in surgical resuscitation

Study Sites (1)

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