Prevention of wound infections after colorectal surgery using antibiotics prior to surgery

Suspended

• Conditions: Surgical site infection; Post procedural wound infection; Postoperative wound infection; Colorectal surgeryDutch: Postoperatieve wondinfectie; Colorectale operatie

• Registration Number: NL-OMON20443
• Lead Sponsor: niversity Medical Center Utrecht

Brief Summary

.A.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Suspended
• Sex: Not specified
• Target Recruitment: 966

Inclusion Criteria

• Patients aged 18 years or older

• Patients undergoing elective colorectal surgery

Exclusion Criteria

• Patients aged <18 years

• Legally incapacitated patients or patients who refuse to sign informed consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The cumulative incidence of deep surgical site infections and/or mortality within 30 days after elective colorectal surgery

Secondary Outcome Measures

Name	Time	Method
1. Deep surgical site infections<br /><br>2. 30-day mortality<br /><br>3. Superficial surgical site infections<br /><br>4. Anastomotic leakage<br /><br>5. Relaparotomy<br /><br>6. Bacteremia<br /><br>7. Infections with highly resistant Enterobacteriaceae (HRE) or Clostridium difficile<br /><br>8. Presence of HRE in intestinal flora<br /><br>9. In-hospital use of antibiotics<br /><br>10. 6-month mortality<br /><br>11. Postoperative length of hospital stay<br /><br>12. Postoperative length of ICU stay<br /><br>13. Quality of life<br /><br>14. In-hospital costs<br>