Preventing severe infection after splenectomy

Recruiting

• Conditions: loss of function of the spleen; splenectomy; 10041641

• Registration Number: NL-OMON29806
• Lead Sponsor: St. Antonius Ziekenhuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 18 June 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 50

Inclusion Criteria

patients who underwent a splenectomy in the period 1995-2005 in the area of Utrecht and are older than 18 years
Patient who are (functional) asplenic because of sickle cell anemia, sferocytosis, ITP or a Hodgkin lymphoma and are older than 18 years

Exclusion Criteria

-Patients who underwent a splenectomy in the period 1995-2005 in the area of Utrecht and are younger than 18 years.
-Patient who are (functional) asplenic because of sickle cell anemia, ITP, sferocytosis or a Hodgkin lymphoma who are younger than 18 years
-Patients who are unable to give informed consent

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>IgG-antibody titer (U/L) against Streptococcus Pneumoniae, Haemophilus<br /><br>influenzae en Neisseria Meningitidis </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>-Percentage of patiënts that is vaccinated against Streptococcus Pneumoniae,<br /><br>Haemophilus influenzae en Neisseria Meningitidis<br /><br>-Percentage of patiënts that is revaccinated against Streptococcus Pneumoniae,<br /><br>Haemophilus influenzae en Neisseria Meningitidis<br /><br>-Percentage of patiënts that is informed about the infectious risks of a<br /><br>(functional) asplenia. </p><br>