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High-definition Surface Electromyography Markers for the Diagnosis of Sarcopenia

Not Applicable
Recruiting
Conditions
Sarcopenia
Registration Number
NCT04987814
Lead Sponsor
Assistance Publique - Hôpitaux de Paris
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
120
Inclusion Criteria

Inclusion Criteria:<br><br> - Patient aged 75 years and over<br><br> - Score =4 on the SARC-F screening questionnaire<br><br> - Enrolled in a social security plan (no AME)<br><br> - Informed and consenting patient<br><br>Exclusion Criteria:<br><br> - BMI =30 kg/m2<br><br> - Untreated/unbalanced endocrinological pathology<br><br> - Myopathy<br><br> - Inflammatory or autoimmune pathology<br><br> - Severe psychiatric pathology or severe cognitive disorders that do not allow the<br> performance of examinations<br><br> - Patients who are dependent for all acts of daily life<br><br> - Patients with a very short life expectancy<br><br> - Recent fracture or trauma of the lower limbs preventing dynamic measurement of<br> HD-sEMG recording<br><br> - Bilateral hip prosthesis<br><br> - Skin problem that may interfere with the recording of surface EMG activity<br><br> - Patient under guardianship / curatorship

Exclusion Criteria

Not provided

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Electromyographic signals of the rectus femoris collected by the HD-sEMG technique
Secondary Outcome Measures
NameTimeMethod
Number of participants with falls. Definition of fallers : at least 1 fall in the last 12 months;Skeletal muscle mass index (SMMI in kg/m2, skeletal muscle mass/height2) collected by DEXA;Grip strength by dynamometer (kg);SPPB score (SHORT PHYSICAL PERFORMANCE BATTERY score);HD-sEMG muscle data, measured during lower limb quadriceps extension by High Definition Surface Electromyography HD-sEMG;Rate of Mortality at 1 month;Muscle and subcutaneous fat thicknesses of the quadriceps in mm
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