Percutaneous sympathetic blockade in complex regional pain syndrome type 1;A prospective clinical investigation on predictors of sympatheticaly maintained pain.
- Conditions
- Complex regional pain syndrome type 1 (CRPS-1)
- Registration Number
- NL-OMON24168
- Lead Sponsor
- Department of Anesthesiology, the Academic Hospital Maastricht
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 124
Inclusion Criteria
Adult (18 years or more) male or female patiënts with CRPS1 as diagnosed by IASP criteria, with a duration of 12 months or less with moderate to severe pain (mean NRS of more than 4 in the previous week as measured 3 times daily in a pain diary with 0=no pain and 10= worst imaginable pain) and one extremity involved.
Exclusion Criteria
1. Patiënts of less than 18 years of age;
2. The existence of significant impairment of blood coagulation or the use of oral anticoagulant medication;
3. Patients suffering from diabetic polyneuropathia;
4. Patients who are unlikely to comply with study requirements;
5. Pregnant women;
6. CRPS1 with a duration of more than 12 months.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain relief in the first week after blockade as measured 3 times daily in a pain diary with 0=no pain and 10= worst imaginable pain.
- Secondary Outcome Measures
Name Time Method The following predictors of pain relief after sympathetic blockade will be measured: <br>1. Pain intensity on a NRS scale of 0 to 10;<br>2. Subjective and objective skin temperature;<br>3. Hyper and hypoesthesia;<br>4. Allodynia;<br>5. Hyper and hypoalgesia;<br>6. The presence of dystonia;<br>7. Tremor and myoclonus.