Identifying Individuals at Risk of Glucocorticoid-Induced Impairment of Bone Disease (RIGID
- Conditions
- Secondary OsteoporosisTherapeutic area: Diseases [C] - Hormonal diseases [C19]
- Registration Number
- CTIS2023-506949-27-00
- Lead Sponsor
- Odense University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- 36
Men and women aged 18-50 years
Uncontrolled thyrotoxicosis, Allergy to prednisolone or one of the excipients, Systematic fungal infections, Vaccination with living or weaken viral or bacterial vaccines in patient who or immunocompromised. In these cases, prednisolone treatment should not be administered two weeks before and after vaccination., Not able to provide informed consent (e.g., dementia, not able to understand Danish). At the information meeting the investigator will make an individual assessment to evaluate whether a potential study participants understand the information., Chronic kidney disease (eGFR <30), Known Cushing’s syndrome, Previous gastric bypass and/or known ongoing malabsorption, Severe covid-19 in the last 3 month (defined as needing dexamethasone treatment), Use of oral or inhaled GCs within the past year, Menopause (defined as 1 year without menstrual bleeding), Pregnancy (defined as elevated HCG), Ongoing infection
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method