To evaluate the relation between two assessment procedures (FVD & VExUS) for predicting organ dysfunction in heart failure patients.
- Conditions
- Health Condition 1: I509- Heart failure, unspecified
- Registration Number
- CTRI/2023/10/058186
- Lead Sponsor
- Dr Vimal Bhardwaj
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Getting admited with a diagnosis of acute heart failure [defined as recent worsening of shortness of breath or oxygen saturation (SpO2) < 90% on room air or orthopnea/paroxysmal nocturnal dypnea (PND) along with an increase in NT proBNP]
1.Need for intubation (or already intubated).
2.Signs or symptoms or markers of hypoperfusion: cold extremities, altered mentation, confusion, oliguria, Lactate > 2 mmol/L.
3.Persistent hypotension (SBP < 90 mmHg).
4.Requirement of two or more vasoactive agents to maintain blood pressure.
5.Requirement for invasive cardiac output monitoring.
6.Requirement for Mechanical Circulatory Support.
7.Heart rate < 40 b.pm or persistent life-threatening arrhythmia.
8.Any associated non-cardiac condition requiring critical care admission.
9.Pulmonary arterial systolic pressure > 55mm/hg by bedside 2d-echocardiography
10.Patients with comfort care directives.
11.Suspected sepsis
12.Pregnancy
13.Liver cirrhosis
14.Severe ascites (Grade 3 Ascites defined as Large or gross ascites with marked abdominal distension)
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare serial FVD and serial VExUS scoring as a predictor of organ dysfunction in acute heart failure patients.Timepoint: Until admitted in IC
- Secondary Outcome Measures
Name Time Method To compare the degree of venous congestion assessed by serial femoral venous Doppler in acute heart failure patients with organ dysfunction.Timepoint: Until admitted in ICU;To determine the correlation between femoral venous Doppler and right ventricular function.Timepoint: Until admitted in ICU;To determine the utility of femoral venous Doppler as a prognostic marker in acute heart failure patients.Timepoint: Until admitted in IC