ISRCTN83081599已完成未知
Post-treatment PLATelet aggregation-guided therapy FOR ST-segment elevation Myocardial infarction: a randomized trial
Clinical Center of Serbia (Serbia)0 个研究点目标入组 632 人开始时间: 2012年5月22日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 632
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Patients with intermediate to high risk for 30-day Major Adverse Cardiac Events (MACE) (RISK-PCI score >3) undergoing primary PCI with stent implantation within 12 hours of the onset of symptoms
- •2. Ability to comply with study protocol
- •3. Negative test for pregnancy for women of childbearing potential before enrollment and agreement to use a reliable method of birth control during the study
排除标准
- •Pre-procedural:
- •1. Any history of hemorrhagic stroke
- •2. Ischemic stroke within 30 days of randomization
- •3. Evidence of active abnormal bleeding within 3 months of randomization
- •4. High risk for bleeding on long-term clopidogrel therapy
- •5. Current therapy with coumadin anticoagulation
- •6. Pregnancy or nursing
- •7. Current enrollment in another investigational drug or device study
- •Procedural:
- •1. Balloon angioplasty without stent placement
- •2. Unsuccessful pPCI (post-procedural TIMI flow 0)
- •Post-procedural:
- •1. Died within 24 hours after loading dose
- •2. Active internal bleeding
- •3. Hemoglobin < 10 g/dL or drop in hemoglobin by =3 g/dL
- •4. Platelet count < 100 000 x 10-9/L.
- •5. Thrombin Receptor Activating Peptide (TRAP) value <500 AU
- •6. Indication for permanent anticoagulant therapy
研究者
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不适用
ACUTE-PRASJPRN-jRCTs031220079Fujimoto Shigeru200