The Clinical Outcome and the Exploration of Related Biomarkers of Target Therapy in Metastasis Colorectal Cancer

• Conditions: Neoplasms, Therapy-Associated

• Registration Number: NCT02523495
• Lead Sponsor: Huazhong University of Science and Technology

Brief Summary

Through clinical observation and data statistics, conclude the clinical outcome of target therapy in metastasis colorectal cancer and explore some biomarkers that relate to target therapy.

Detailed Description

1. Establish a clinical database of patients who are diagnosed with metastasis colorectal cancer in tongji hospital.

2. Build a biological specimen banks of metastasis colorectal cancer through collecting blood samples from those patients who have reached an agreement with us.

3. Through clinical observation and data statistics, conclude the clinical outcome of target therapy in metastasis colorectal cancer.

4. To extract DNA from the blood and explore some biomarkers that related to target therapy in metastasis colorectal cancer.

Study Timeline

• Study Start: 2012-06
• Study First Submitted: 2015-08-04
• Study First Submitted QC: 2015-08-12
• Study First Posted: 2015-08-14
• Status Verified: 2018-08
• Last Update Submitted: 2018-08-05
• Last Update Posted: 2018-08-07
• Primary Completion: 2020-07
• Study Completion: 2022-07

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

1. Metastasis colorectal cancer confirmed by histologically and radiography
2. Receive target therapy over half a year
3. Have a measurable lesions

Exclusion Criteria

1. A history of other malignant tumors in five years

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
overall survival	5 years

Trial Locations

Locations (1)

Huazhong University of Science and Technology; 🇨🇳 Wuhan, Hubei, China