Changes in troponin for diagnosis of acute myocardial infarction (AMI) in an emergency department (ED) population with chest pain.

Not Applicable

Completed

• Conditions: Acute coronary syndrome; Cardiovascular - Coronary heart disease

• Registration Number: ACTRN12610000052033
• Lead Sponsor: Queensland Emergency Medicine Research Foundation QEMRF

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-01-18
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 650

Inclusion Criteria

Inclusion criteria include all patients who present to the emergency departmetn (ED)with at least 5 minutes of chest pain suggestive of acute coroanry syndrome (ACS). In accord with American Heart Association (AHA) guidelines, these will include the presence of acute chest, epigastric, neck, jaw or arm pain or discomfort or pressure or breathlessness without apparent non-cardiac source. More general/atypical symptoms (such as fatigue, nausea, vomiting, sweating and faintness) will not be used as inclusion criteria.

Patients who have chest discomfort and in whom the attending staff consider it necessary to perform an Electrocardiogram (ECG) for the assessment of possible ACS will be enrolled.

Exclusion Criteria

Pregnancy
Patients under the age of 18 years old
Unable or unwilling to consent
Patients for whom follow-up will not be possible either due to lack of contact address or because they will be overseas.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
AMI as adjudicated by cardiologists as an endpoint.[Within 24 hours of presentation to ED]

Secondary Outcome Measures

Name	Time	Method
Alternative diagnosis with raised TnI - as adjudicated by cardiologists.[Within 24 hours of presentation to ED]