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Effect of a Sequence of Specific Manual Therapy Techniques Targeting the Autonomic Nervous System in Healthy Adults

Not Applicable
Recruiting
Conditions
Autonomic Imbalance
Interventions
Procedure: Simulated manual therapy techniques
Procedure: Sequence of manual therapy techniques
Registration Number
NCT06477822
Lead Sponsor
Universitat Internacional de Catalunya
Brief Summary

The activity of the autonomic nervous system has been shown to influence the appearance of symptoms in some diseases such as rheumatoid arthritis, fibromyalgia, or migraine, among others. In the bibliography we find different authors who, through intervention using manual therapy, have demonstrated its effects on the autonomic nervous system, especially on the increase in parasympathetic activity and reduction in sympathetic activity. A clinical trial is proposed to verify these effects.

Detailed Description

The aim of the study is to analyse the effects of applying a specific sequence of manual therapy techniques focused on the regulation of the autonomic nervous system. This intervention sequence will be applied in a single intervention. As a result, an immediate increase in parasympathetic activity could occur, measured by different parameters of heart rate variability, heart rate and respiratory rate. If the results confirm the expected effects, this treatment sequence could be used as a therapeutic resource in patients with pathologies whose symptoms may be related to the deregulation of the autonomic nervous system, such as rheumatoid arthritis, migraine or fibromyalgia, among others.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
96
Inclusion Criteria
  • Provision of informed consent
  • Aged between 18-65
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Exclusion Criteria
  • Regular consumtion of alcohol or illegal drugs
  • Consumption of medications whose effect acts on the autonomic nervous system (cholinergic agonists and antagonists, or adrenergic agonists and antagonists)
  • Diagnostic of disease that may affect the activity of the autonomic nervous system or the perception of pain (such as generalized anxiety disorder, fibromyalgia, or chronic fatigue).
  • Pregnancy
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Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Simulated manual therapy techniquesSimulated manual therapy techniquesParticipants receive a sequence of simulated manual therapy techniques
Sequence of manual therapy techniquesSequence of manual therapy techniquesParticipants receive a manual therapy secuence of techniques
Primary Outcome Measures
NameTimeMethod
Heart rateDay 1

The investigators will examine the difference between Time 1 and Time 2 and between groups in beats per minute.

Root mean square of the successive differences between adjacent RR intervals (RMSSD) in heart rate variability indexDay 1

The investigators will examine the difference between Time 1 and Time 2 and between groups in HRV measured by Root mean square of the successive differences between adjacent RR intervals (RMSSD) in heart rate variability index

Secondary Outcome Measures
NameTimeMethod
Incidence of Treatment-Emergent Adverse EventsDay 1

The investigators register if an adverse effect is present during the intervention or just after the intervention.

Respiratory rateDay 1

The investigators will examine the difference between Time 1 and Time 2 and between groups in breaths per minute.

High frequency (HF) band in heart rate variability indexDay 1

The investigators will examine the difference between Time 1 and Time 2 and between groups in HRV measured by high frequency (HF) band in heart rate variability index .

Trial Locations

Locations (1)

Universitat Internacional de Catalunya

🇪🇸

Sant Cugat Del Vallès, Barcelona, Spain

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