Effect of a Sequence of Specific Manual Therapy Techniques Targeting the Autonomic Nervous System in Healthy Adults
- Conditions
- Autonomic Imbalance
- Interventions
- Procedure: Simulated manual therapy techniquesProcedure: Sequence of manual therapy techniques
- Registration Number
- NCT06477822
- Lead Sponsor
- Universitat Internacional de Catalunya
- Brief Summary
The activity of the autonomic nervous system has been shown to influence the appearance of symptoms in some diseases such as rheumatoid arthritis, fibromyalgia, or migraine, among others. In the bibliography we find different authors who, through intervention using manual therapy, have demonstrated its effects on the autonomic nervous system, especially on the increase in parasympathetic activity and reduction in sympathetic activity. A clinical trial is proposed to verify these effects.
- Detailed Description
The aim of the study is to analyse the effects of applying a specific sequence of manual therapy techniques focused on the regulation of the autonomic nervous system. This intervention sequence will be applied in a single intervention. As a result, an immediate increase in parasympathetic activity could occur, measured by different parameters of heart rate variability, heart rate and respiratory rate. If the results confirm the expected effects, this treatment sequence could be used as a therapeutic resource in patients with pathologies whose symptoms may be related to the deregulation of the autonomic nervous system, such as rheumatoid arthritis, migraine or fibromyalgia, among others.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 96
- Provision of informed consent
- Aged between 18-65
- Regular consumtion of alcohol or illegal drugs
- Consumption of medications whose effect acts on the autonomic nervous system (cholinergic agonists and antagonists, or adrenergic agonists and antagonists)
- Diagnostic of disease that may affect the activity of the autonomic nervous system or the perception of pain (such as generalized anxiety disorder, fibromyalgia, or chronic fatigue).
- Pregnancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Simulated manual therapy techniques Simulated manual therapy techniques Participants receive a sequence of simulated manual therapy techniques Sequence of manual therapy techniques Sequence of manual therapy techniques Participants receive a manual therapy secuence of techniques
- Primary Outcome Measures
Name Time Method Heart rate Day 1 The investigators will examine the difference between Time 1 and Time 2 and between groups in beats per minute.
Root mean square of the successive differences between adjacent RR intervals (RMSSD) in heart rate variability index Day 1 The investigators will examine the difference between Time 1 and Time 2 and between groups in HRV measured by Root mean square of the successive differences between adjacent RR intervals (RMSSD) in heart rate variability index
- Secondary Outcome Measures
Name Time Method Incidence of Treatment-Emergent Adverse Events Day 1 The investigators register if an adverse effect is present during the intervention or just after the intervention.
Respiratory rate Day 1 The investigators will examine the difference between Time 1 and Time 2 and between groups in breaths per minute.
High frequency (HF) band in heart rate variability index Day 1 The investigators will examine the difference between Time 1 and Time 2 and between groups in HRV measured by high frequency (HF) band in heart rate variability index .
Trial Locations
- Locations (1)
Universitat Internacional de Catalunya
🇪🇸Sant Cugat Del Vallès, Barcelona, Spain