Efficacy of Incentive Spirometer and Diaphragmatic Breathing Exercise on the Alteration of Arterial Blood Gas Measures in Patients After Coronary Artery Bypass Grafting. A Randomized Comparative Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Partial pressure of Arterial Oxygen molecule (PaO2)
研究概览
简要总结
The rate of pulmonary complications following Coronary artery bypass graft (CABG) is high. Early pulmonary exercises are important in preventing this complication following cardiac surgery. This study aimed to investigate the effectiveness of incentive spirometer (IS) and diaphragmatic breathing exercise (DBE) on the alteration of arterial blood gas (ABG) measures. The study was based on a two-arm, parallel-group, randomized comparative design. Thirty patients who underwent CABG enrolled in the study based on inclusion and exclusion criteria, randomly allocated into either of the groups, IS Group or DBE Group. IS Group and DBE Group underwent chest physiotherapy with IS and DBE, respectively. ABG measures, including PH of blood, partial pressure of arterial oxygen molecule (PaO2), and partial pressure of arterial carbon dioxide (PaCO2), was assessed using an ABG analyzer at baseline (pre-operation), day1 post-operation, and day2 post-operation. The significance level was kept constant for all statistical analyses at 95%.
详细描述
Coronary artery bypass graft (CABG) is one of common treatment procedures performed worldwide. Evidence suggest that every year more than 1 million CABG procedure has been performed. Pulmonary complications are one of the most common consequence post CABG.
The incidence of atelectasis after heart operation with cardiopulmonary bypass is still 80-84% in spite of careful fluid & respiratory management. The basic problem in respiratory care of post-surgical patient is atelectasis leading to hypoxemia causing alteration in arterial blood gases (ABGs). Associated with atelectasis are widening alveolar - arterial O2 gradient (as right to left intrapulmonary shunting increases) decrease ventilation perfusion ratio, decrease functional residual capacity and decrease compliance. Chest physiotherapy is routinely used after major abdominal & cardiothoracic surgery to prevent these pulmonary complications following operation.
To date, there is a variable view about the effectiveness of these two primary breathing exercise techniques (incentive spirometer and diaphragmatic breathing exercise). 10-12 Hence an effort to systematically study the effectiveness of these is attempted. Thus, the current study aimed to determine the efficacy of incentive spirometer and diaphragmatic breathing exercises in addition to conventional chest physiotherapy on alteration of ABG measures in patients with post CABG. This study hypothesized that there will be a significant difference between the effect of the IS and DBE on ABG alteration in post CABG patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 40 Years 至 60 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The patient with post-CABG,
- •Aged between 40 and 60 years,
- •Had forced expiratory volume in 1 second (FEV1) <70% of predicted value,
- •Showed FEV1/forced vital capacity (FVC) ratio >0.8,
- •Weight equal or exceeded the ideal body weight by less than 20%, and
- •Patient co-operation.
排除标准
- •Aged more than 60 years,
- •Weight equal or exceeded the ideal body weight by more than 20%,
- •Post-operative respiratory treatment exceeding 20 hours,
- •History of Chronic obstructive pulmonary disease (COPD) /thoracic surgery including CABG,
- •had thoracic anomalies/unstable angina,
- •Developed hemodynamic complication, and
- •Non-cooperative/neurological debilitated patient.
结局指标
主要结局
Partial pressure of Arterial Oxygen molecule (PaO2)
时间窗: 3 Days
PaO2 was assessed using an ABG analyzer machine
PH of Blood
时间窗: 3 Days
PH of blood was assessed using an ABG analyzer machine
Partial pressure of Arterial Carbon dioxide molecule (PaCO2)
时间窗: 3 Days
PaCO2 was assessed using an ABG analyzer machine
次要结局
未报告次要终点
研究者
AMIR IQBAL
Prinicipal Investigator
King Saud University
