Dengue Severity in Children: Detecting Warning Signs through Proteinuria and Gall Bladder Health
Not Applicable
- Conditions
- Health Condition 1: A90- Dengue fever [classical dengue]
- Registration Number
- CTRI/2023/05/052808
- Lead Sponsor
- niversity College of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Probable dengue and confirmed dengue as per WHO 2020 guidelines
Exclusion Criteria
1.Patients of dengue without warning signs
2.Patients who get admitted at or after day 7 of fever.
3.Pediatric patients with diagnosed nephrotic syndrome, acute glomerulonephritis, acute renal failure, tubulo interstitial disease, Immune mediated nephritis.
4.Patients with associated hypoalbuminemia, metabolic disorders, trauma, malignant disease, vascular problems, acute hepatitis, acute pancreatitis
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Spot urine albumin creatinine ratio <br/ ><br>Gall bladder wall thickness (higher or lower) <br/ ><br>Timepoint: Spot urine albumin creatinine ratio: at admission, and on day 7 <br/ ><br>Gall bladder wall thickness (higher or lower): between day 3 and 6 of thickness <br/ ><br> <br/ ><br>
- Secondary Outcome Measures
Name Time Method 1.The association of urine albumin creatinine ratio with laboratory parameters (Hematocrit and platelet count) <br/ ><br>2.The association of gall bladder wall thickness with laboratory parameters (Hematocrit and platelet count). <br/ ><br>3.Distribution of different patterns of gall bladder wall thickness in different severity groups of dengue . <br/ ><br>Timepoint: 1,2:The association of urine albumin creatinine ratio and gall bladder wall thickness with laboratory parameters (Hematocrit and platelet count): at admission and at discharge <br/ ><br>3.Distribution of different patterns of gall bladder wall thickness in different severity groups of dengue: between day 3 and day 6 ofillness <br/ ><br>