Randomized Controlled Trial Comparing Postoperative Pain Following TAH With GA vs. Combined GA + SAB

Not Applicable

Withdrawn

• Conditions: Hysterectomy
• Interventions: Drug: General Anesthesia + Spinal anesthesia combined; Drug: General Anesthesia (control group)

• Registration Number: NCT01511627
• Lead Sponsor: University of Saskatchewan

Brief Summary

The investigators hypothesize that a spinal anesthetic administered prior to the induction of general anesthesia will result in reduced need for pain medication and reduced postoperative pain, as well as reduced hospital stay following a total abdominal hysterectomy.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-01
• Study First Submitted: 2012-01-09
• Study First Submitted QC: 2012-01-17
• Study First Posted: 2012-01-18
• Primary Completion: 2012-07
• Study Completion: 2012-07
• Status Verified: 2016-11
• Last Update Submitted: 2016-11-10
• Last Update Posted: 2016-11-15

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

• American Society of Anesthesiologists' (ASA) I and II patients undergoing elective Total Abdominal Hysterectomy at the Saskatoon City Hospital
• Lower transverse abdominal incision

Exclusion Criteria

• BMI > 40
• The TAH is treatment for cancer
• A history of regular opioid use
• Any medical condition that would make a spinal inadvisable,
• An allergy or medical condition that would make it inadvisable to receive the drugs used in this study (eg. Peptic ulcer disease), or
• If you will also be having a salpingo-oophorectomy).

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
General Anesthesia + Spinal Anesthesia	General Anesthesia + Spinal anesthesia combined	-
General Anesthesia	General Anesthesia (control group)	-

Primary Outcome Measures

Name	Time	Method
Total Morphine consumption	Post-operative day 2	The primary outcome will be total opioid use per day, as recorded by the PCA pump and transcribed by the nursing staff in the PACU and on the post-operative ward.
Morphine consumption	1 day	The primary outcome will be total opioid use per day, as recorded by the PCA pump and transcribed by the nursing staff in the PACU and on the post-operative ward.

Secondary Outcome Measures

Name	Time	Method
Pain score on the VAS	On post-operative day 2 at 22:00

Trial Locations

Locations (1)

Saskatoon City Hospital; 🇨🇦 Saskatoon, Saskatchewan, Canada