Bioavailability of calcium and magnesium from mineral water

Not Applicable

• Conditions: calcium and magnesium undersupply; E61.2; E58; Magnesium deficiency; Dietary calcium deficiency

• Registration Number: DRKS00010411
• Lead Sponsor: Gesellschaft der Freunde und Förderer der deutschen Mineralbrunnenindustrie e.V.

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2016-04-18
• Study Completion: 2016-06-08
• Results First Posted: 2017-06-19
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 43

Inclusion Criteria

competent men and women aged 18-50 years; BMI range between 18,5-29,9 kg/m²; Ability and willingness of study participants to follow study leaders instructions (Compliance to study procedure, intake of study products according to intake recommendations, etc.), written consent after information about study contents, procedure and risks

Exclusion Criteria

allergies regarding study product contents; intake of dietary supplements and / or drugs containing calcium or / and magnesium during study phase; severe chronic illness (Diabetes mellitus Typ I, kidney diseases, liver diseases, manifested coronary diseases, cancer); coagulation dysfunctions as well as intake of anticoagulating drugs e.g. Marcumar (exeptional case: ASS); chronic gastrointestinal diseases (colitis ulcerosa, morbus crohn, pancreas insufficiency); regularly intake of laxative medicines; pregnancy or lactation; addiction to alcohol and/or drugs; missing consent or refusing / reset of the consent; participation in another clinical study at the same time or within past 30 days; planned surgery within the next 3 month

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Calcium (blood parameter) at time 1 hour after beginning, 2 hours after beginning, 3 hours after beginning, 4 hours after beginning, 5 hours after beginning, 6 hours after beginning, 8 hours after beginning, 10 hours after beginning; <br>Magnesium (blood parameter) at time 1 hour after beginning, 2 hours after beginning, 3 hours after beginning, 4 hours after beginning, 5 hours after beginning, 6 hours after beginning, 8 hours after beginning, 10 hours after beginning

Secondary Outcome Measures

Name	Time	Method
rinary calcium at time 0 (start measurement), 0-2 hours after beginning, 2-4 hours after beginning, 4-6 hours after beginning, 6-8 hours after beginning, 8-12 hours after beginning, 12-24 hours after beginning;<br>Urinary magnesium at time at time 0 (start measurement), 0-2 hours after beginning, 2-4 hours after beginning, 4-6 hours after beginning, 6-8 hours after beginning, 8-12 hours after beginning, 12-24 hours after beginning