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临床试验/CTRI/2024/12/078651
CTRI/2024/12/078651尚未招募不适用

A CLINICAL STUDY TO EVALUATE THE EFFICACY OF AGNIKARMA WITH GODANTA AND SIRAVEDH IN THE MANAGEMENT OF KITIBHA KUSHTA WITH SPECIAL REFERENCE TO PSORIASIS IN AGE GROUP OF 18-70 YEARS

DMM Ayurved Mahavidyalaya,Yavatmal1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2025年1月7日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
40
试验地点
1
主要终点
The parameters will be noted down before and after treatment,The patient will be diagnosed based on symptoms of Kitibha kushta (Psoriasis) explained in Ayurvedic and Modern texts.

研究概览

简要总结

Ayurveda is “the science of life”. Ayurveda is not only curative but also preventive science of life. Ayurveda has 8 branches (Astang Ayurveda). Shalyatantra is one of the important branch of Ashtanga Ayurveda in which surgical and para-surgical techniques are described for various diseases. In healthcare sector tremendous research has been conducted to treat different types of skin disease. In Ayurveda, The word Kushta is broad term, which covers almost all skin disorders. “कष्णाती इतत कष्ठम” (मा.ति./कष्ठ/टीका 1)  According to Ashtang hrudaya,in kushta due to vitiated dosha the part of skin becomes affected and changes its normal colour called kushtha. Ayurveda has given importance to skin disease and reference of kushtha can be found since vedic period. This Kitibha Kushtha can be co-related to psoriasis in clinical features has been classified and explained under kshudra kushta. Ayurvedic classics have considered each type of Kustha to be a Tridosaja manifestation. Their Doshik identity can be established on the basis of dominance of Dosha in the Samprapti. Thus Kitibhakustha is Vata-Kaphaja The signs and symptoms of psoriasis resemble with those of vatakapha dushti. Among vatakaphaj kushtha types, kitibh kushtha is most similar in presentation. So by using the law of “Vyapadeshastu bhuyasa”, Psoriasis can be correlated with kitibh kushtha Psoriasis is one amongst these notorious auto-immune disorders having deep psychological and social impacts. It is a chronic inflammatory disease with skin manifestations, aggravated by or can recur by number of triggering factors such as psychological,dietary, environmental changes, medications, etc. The prevalence of Psoriasis is raising an alarming picture, as presently about 120-180 million of global population suffer from Psoriasis. Agnikarma is a unique procedure where heat is conducted to the affected tissue with help of variety of materials.

A fire (cautery) is better than Alkali as far as its healing property is concerned. A disease burnt with fire, is cured for good and knows no recrudescence; It enjoys the label of ‘Apunarbhav Chikitsa’, i.e. diseases cured by this process are uprooted radically!

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • Age group above 18 years and below 70 years.
  • Patient having classical signs and symptoms of kitibh kushta.
  • Patient willing for clinical trial.
  • Irrespective of gender, occupation, Religion, economical Barrier.
  • Patient willing to participate.
  • Patient who will fulfil criteria with regular follow up.

排除标准

  • Age group below 18 years and above 70 years.
  • Pregnant and lactating mother.
  • Infective origins like Scabies,Fungal infection,herpes zoster.
  • Immune compromised like HIV 5) Diabetic person 6) Patient having cardiac disease 7) Renal diseases.

结局指标

主要结局

The parameters will be noted down before and after treatment,The patient will be diagnosed based on symptoms of Kitibha kushta (Psoriasis) explained in Ayurvedic and Modern texts.

时间窗: Method 1 : Agnikarma with Godanta will be done On | 1St,14th,28th day | Method 2 : Siravedh On | 7th,21st,35th day | Follow up on 42th day

1) Kinakhara sparsha (Scaling)

时间窗: Method 1 : Agnikarma with Godanta will be done On | 1St,14th,28th day | Method 2 : Siravedh On | 7th,21st,35th day | Follow up on 42th day

2) Shyawam (Greyish Discolouration)

时间窗: Method 1 : Agnikarma with Godanta will be done On | 1St,14th,28th day | Method 2 : Siravedh On | 7th,21st,35th day | Follow up on 42th day

3) Parusha (Dryness)

时间窗: Method 1 : Agnikarma with Godanta will be done On | 1St,14th,28th day | Method 2 : Siravedh On | 7th,21st,35th day | Follow up on 42th day

4) Sravi(Discharge),

时间窗: Method 1 : Agnikarma with Godanta will be done On | 1St,14th,28th day | Method 2 : Siravedh On | 7th,21st,35th day | Follow up on 42th day

5) Vritta (Oval to round Lesions)

时间窗: Method 1 : Agnikarma with Godanta will be done On | 1St,14th,28th day | Method 2 : Siravedh On | 7th,21st,35th day | Follow up on 42th day

6) Ghana(Elevation)

时间窗: Method 1 : Agnikarma with Godanta will be done On | 1St,14th,28th day | Method 2 : Siravedh On | 7th,21st,35th day | Follow up on 42th day

7) Ugrakandu (Severe pruritis)

时间窗: Method 1 : Agnikarma with Godanta will be done On | 1St,14th,28th day | Method 2 : Siravedh On | 7th,21st,35th day | Follow up on 42th day

次要结局

  • All parameters will be assessed before and after treatment. 1) No improvement – 0 % relief in signs and symptoms. 2) Poor improvement – 0%-25% relief in sign and symptoms 3) Mild improvement – 26% to 50% improvement in signs and symptoms 4) Moderate improvement – 51% to 75 % improvement in signs and symptoms 5) Marked improvement – 76% to 100% improvement in signs and symptoms.(Method 1 : Agnikarma with Godanta will be done On)

研究者

发起方
DMM Ayurved Mahavidyalaya,Yavatmal
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Dr Akash Anantrao Bhojane

DMM Ayurved Mahavidyalaya Yavatmal

研究点 (1)

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