Decannulation of Tracheostomy Cannula Based on Suctioning Frequency and High-flow Oxygen Protocol in the Intensive Care Unit
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Time to decannulation
研究概览
简要总结
In the DECAP-ICU trial, the investigators will be focusing on the impact of a new weaning tracheostomy technique based on suctioning frequency compared to the standard practice of capping tolerance.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
盲法说明
None, patients and physicians will know the protocol
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Weaning from mechanical ventilation for at least 24 hours
- •Randomisation must be done in 24 hours of the mechanical ventilation weaning.
排除标准
- •Sabadell > 2
- •Contraindication of decannulation : Glasgow Coma Scale <6, severe dysphagia, non permeable respiratory tracks, neuromuscular disease (expect for the ICU weakness) and long term tracheostomy.
研究组 & 干预措施
Usual care
Usual care will mainly base on the capping trial.
干预措施: Usual Care (Procedure)
Suction based protocol
Weaning protocol based on suctioning frequency. Once the weaning of mechanical ventilation, the patients in this arm will be on high-flow nasal canula. The canula will be remove if the decannulation conditions are met (if the patient require less than 2 aspirations in 8 hours for 24 consecutive hours)
干预措施: Suctioning based protocol (Procedure)
结局指标
主要结局
Time to decannulation
时间窗: Frome date of randomisation to the date of the actual decannulation or to the date of death, whichever comes first, assessed up to 48 months.
Time between the randomisation and the decannulation
次要结局
- Time to decannulation criteria(From date of randomisation to the date when the criteria of decannulation are met or to the date of death, whichever comes first, assessed up to 48 months.)
- Length of stay hospital(From admission to the date when the patient is discharge of the hospital, through study completion, average of 6 to 12 months.)
- Length of stay ICU(From admission to the date when the patient quit the ICU, through study completion, average of 6 to 12 months.)
- ICU readmission(Through study completion, average of 6 to 12 months.)
- Decannulation failure(Through study completion, average of 6 to 12 months.)
- Mechanical Ventilation weaning failure(Through study completion, average of 6 to 12 months.)
- Adverses effects(Through study completion, average of 6 to 12 months.)
- Mortality(Through study completion, average of 6 to 12 months.)