Diastolic Dysfunction PPCM in Patients With Documented Left Ventricular Systolic Function Recovery

Withdrawn

• Conditions: Diastolic Dysfunction; Peripartum Cardiomyopathy
• Interventions: Diagnostic Test: A clinical Transthoracic echocardiogram

• Registration Number: NCT04143997
• Lead Sponsor: Medical College of Wisconsin

Brief Summary

The purpose of this project is to evaluate parameters of diastolic dysfunction assessed by clinical echocardiogram in patients who have had recovery of systolic function.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2019-10-28
• Study First Submitted QC: 2019-10-28
• Study First Posted: 2019-10-30
• Study Start: 2019-11-01
• Primary Completion: 2021-01-29
• Study Completion: 2021-01-29
• Status Verified: 2024-08
• Last Update Submitted: 2024-08-21
• Last Update Posted: 2024-08-23

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

1. Female.
2. Greater than age 18 years at the time of peripartum cardiomyopathy diagnosis.
3. Adults with a current or prior diagnosis of peripartum cardiomyopathy and documented recovered of left ventricular systolic function.
4. Documented recovered of LV systolic performance defined as LVEF > 50%.

Exclusion Criteria

1. No pregnancy history.
2. No diagnosis of peripartum cardiomyopathy.
3. Non-recovery of LV systolic function.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
PPCM with Diastolic Dysfunction & Normal Systolic Function	A clinical Transthoracic echocardiogram	The patient population examined will include patients diagnosed with peripartum cardiomyopathy who have diastolic dysfunction and normal systolic function.

Primary Outcome Measures

Name	Time	Method
Report the incidence of diastolic dysfunction in peripartum cardiomyopathy patients with full systolic function recovery	January 1, 2014 through September 1, 2019	Investigators will review and report incidence of remaining diastolic dysfunction for local patient population which have recovered systolic function.

Trial Locations

Locations (1)

Medical College of Wisconsin; 🇺🇸 Milwaukee, Wisconsin, United States