Petechiae In Children (PIC) Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,329
- 试验地点
- 1
- 主要终点
- Confirmation of meningococcal infection
研究概览
简要总结
A fever and a non-blanching rash is a relatively common reason for a child to attend an emergency department. A fever and a non-blanching rash can be an early sign of a life-threatening infection known as meningococcal disease. The aim of the PIC study is to determine how best to diagnose early meningococcal disease in children.
In particular the investigators are interested in researching how quick bedside tests can be used to do this.
详细描述
A fever an a non-blanching rash is a relatively common presentation the the emergency department. A minority of children with a fever and a non-blanching rash with have a life-threatening infection. Currently it is very difficult to determine those children that require urgent treatment from those that have a simple viral illness.
The aim of the PIC study is to research how to better diagnose those serious infections earlier.
Data from the study will be used to test the effectiveness of current practice and to identify areas where current practice could be improved.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- — 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Fever (recorded or reported) 38 degrees Centigrade or higher and a non-blanching rash (at the time of presentation)
- •Features of meningococcal sepsis/meningitis
排除标准
- •Known haematological conditions such as haematological malignancy, idiopathic thrombocytopenic purpura and coagulopathy
结局指标
主要结局
Confirmation of meningococcal infection
时间窗: 72 hours from testing
Blood and Cerebrospinal fluid (CSF) culture or quantitative Polymerase Chain Reaction (PCR) will be used to confirm meningococcal infection
次要结局
未报告次要终点