The Impact of Combined Modality Therapy on Sensorineural Hearing Loss in Patients with Head and Neck Cancer

Not Applicable

• Conditions: Head and Neck Cancer; Sensorineural Hearing Loss; Cancer - Head and neck; Ear - Other ear disorders

• Registration Number: ACTRN12615001300561
• Lead Sponsor: Phoebe Shorter

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-11-30
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Histopathologically confirmed head and neck squamous cell carcinoma; all mucosal primary subsites accepted
Tumour classified as stage II – IV, according to the TNM classification
The patient must be a candidate for combined modality therapy, in either the definitive or postoperative setting
The patient must be booked to received external beam radiotherapy at the Princess Alexandra Hospital
Has provided written, informed consent for participation in the study

Exclusion Criteria

Distant Metastases
Palliative Radiotherapy
Extension of disease into the auditory system
Previous external beam radiotherapy to the head and neck region
Incomplete radiotherapy or absence of baseline audiology testing
Pre-existing otological condition (i.e Meniere’s disease) that may influence the outcome of audiological assessment
The patient should not be in state or condition that is expected to influence the outcome of treatment, complicate the audiological assessment or follow-up, or reduce life expectancy (apart from the present disease)
Sufficient proficiency in English, cognitive capacity and willingness to complete questionnaires
Pregnant

Study & Design

• Study Type: Interventional
• Study Design: Not specified