se of Dry Powder Mannitol for the Treatment of Chronic Rhinosinusitis

Phase 3

• Conditions: Chronic rhinosinusitis; Respiratory - Other respiratory disorders / diseases; Inflammatory and Immune System - Other inflammatory or immune system disorders

• Registration Number: ACTRN12612001008819
• Lead Sponsor: Dr Emad Massoud

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-09-19
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Patients with chronic rhinosinusitis (as defined by the Canadian clinical practice guidelines for acute and chronic sinusitis)

Exclusion Criteria

Previous sinus surgery
Allergy or sensitivity to any of the items in the standard medical treatment

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
We will be looking at 3 different parameters:<br>1. symptom control as per the symptom questionnaire Sino-Nasal Outcome Test (SNOT)-22.[every 6 weeks for a period of 6 months]

Secondary Outcome Measures

Name	Time	Method
2. improvement in the status of the lining of the nose and paranasal sinus lining as per the examination standardized scoring system (Lund/Kennedy Score).[every 6 weeks for a period of 6 months];3. improvement in the scoring for the CT scan of the nose and paranasal sinuses before and after treatment (Lund/MacKay Score).[every 6 weeks for a period of 6 months]