FiO2 in Chronic Obstructive Pulmonary Disease (COPD) Patient Normobaric O2 Versus NIV
- Conditions
- COPDHome CareOxygen Therapy
- Registration Number
- NCT02599246
- Lead Sponsor
- Breas Medical S.A.R.L.
- Brief Summary
The purpose of this study is to compare pharyngeal FiO2 in day time with nasal normobaric O2 with inhaled FiO2 in the night time with home care ventilator NIV at the same O2 flow.
- Detailed Description
in a prospective observational study the investigators will register FiO2 in 15 voluntaries COPD patients as following:
* Pharyngeal FiO2 (G5® Philips™ side stream FiO2) with O2 supply through nasal cannula at basal flow (flow needed by patient). In order to compare FiO2s the investigators will measure FiO2 with 150%, 75%, 50% and 25 % of basal Flow
* And FiO2 during nocturnal NIV (pressure support ventilation; Vivo 50®, Bréas™), using facial or nasal masque (Confort Gel® Respironics™). O2 flow will be basal flow.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 14
- informed consent
- acute on chronic respiratory distress
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Difference in FiO2 measured during NIV compared to the FiO2 measured during day time with nasal canula at similar O2 flow 18 hours
- Secondary Outcome Measures
Name Time Method Time spent below different O2 levels during NIV despite constant O2 flow and their correlation to day time FiO2 with nasal canula 18 hours levels of O2 adjustment needed to keep FiO2 stable with NIV 1 hour
Trial Locations
- Locations (1)
Military teaching hospital Ste Anne
🇫🇷Toulon, VAR, France