Comparing Therapeutic effects of combination of high volume normal saline and salbutamol nebulizer with combination of hypertonic saline 3% and salbutamol nebulizer in bronchiolitis treatment

Phase 3

• Conditions: Bronchiolitis.; Other acute lower respiratory infections; J20, J21,J

• Registration Number: IRCT2016022826809N1
• Lead Sponsor: Vice chancellor for research,Zahedan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 180

Inclusion Criteria

age less than 2 year old; history of recent upper respiratory viral infection which caused wheeze and crackle in auscultation; CBSS 4-8 in admit. Exclusion criteria: age less than 1 month or more than 2 years old; history of recurrent attack of wheeze; sever neurological disorder; consolidation in Chest x ray; immune deficiency; congenital heart disease; history of premature (gestational age less than 34 weeks); birth weight less than 2500 gr; saturation of oxygen less than 85% in room; CBSS less than 4 or more than 8; unstable hemodynamic (heart rate more than 200 per minute, blood pressure 2 standard deviation more or less than normal range for age and sex, respiratory rate more than 70 per minute).

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Respiratory rate. Timepoint: Pretreatment and each 30 minute up to 3 times after the begining of treatment. Method of measurement: Counting respiratory rate in 1 minute.;O2 saturation. Timepoint: Pretreatment and each 30 minute up to 3 times after the begining of treatment. Method of measurement: Pulse oximetery.;Heart rate. Timepoint: Pretreatment and each 30 minute up to 3 times after the begining of treatment. Method of measurement: Counting heart rate in 1 minute.;Intercostal retraction. Timepoint: Pretreatment and each 30 minute up to 3 times after the begining of treatment. Method of measurement: Physical exam and score of CBSS (0,1,2,3).;Dyspnea. Timepoint: Pretreatment and each 30 minute up to 3 times after the begining of treatment. Method of measurement: Physical exam and score of CBSS (0,1,2,3).;Wheezing. Timepoint: Pretreatment and each 30 minute up to 3 times after the begining of treatment. Method of measurement: Physical exam and score of CBSS (0,1,2,3).