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Clinical Trials/NCT05677165
NCT05677165CompletedNot Applicable

The Relationship Between Driving Pressure, Mechanical Power, Oxygenation and Saturation Indices: Retrospective Observational Study

Bakirkoy Dr. Sadi Konuk Research and Training Hospital1 site in 1 country361 target enrollmentStarted: March 18, 2020Last updated:
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Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Enrollment
361
Locations
1
Primary Endpoint
In hospital mortality
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

By using Mechanical Power and Driving Pressure instead of Pmean we calculate new oxygen saturation indices like Driving Pressure Oxygen Index (OIDP), Dynamic Power Oxygen Index (OIMPdyn), Total Power Oxygen Index (OIMPtot), Driving Pressure Saturation Index (OSIDP), Dynamic Power Saturation Index (OSIMPdyn) ve Power Saturation Index (OSIMPtot).

New oxygenation and saturation indices are able to predict ICU mortality better than the conventional indexes and rates.

Study Design

Study Type
Observational
Observational Model
Other
Time Perspective
Retrospective

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • •Patients with a diagnosis of Covid-19 related Acute Respiratory Syndrome (C-ARDS) which hospitalized in Bakirköy Dr. Sadi Konuk Training and Research Hospital intensive care unit

Exclusion Criteria

  • •Patients who did not receive invasive mechanical ventilation support.
  • •Patients who stayed in the intensive care unit for less than 24 hours.
  • •Patients with missing data
  • •Patients who received mechanical ventilation support for less than 24 hours
  • •Patients with Chronic Obstructive Pulmonary Disease (COPD).
  • •Patients with congestive heart failure
  • •Patients who underwent tube thoracostomy due to tension pneumothorax
  • •Patients who received Extracorporeal Membrane Oxygenation (ECMO) support

Outcomes

Primary Outcomes

In hospital mortality

Time Frame: 28 days

we estimate hospital mortality mortality by calculating new oxygenation index

Secondary Outcomes

  • Mechanical ventilatory free days(30 days)

Investigators

Sponsor
Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Sponsor Class
Other Gov
Responsible Party
Sponsor

Study Sites (1)

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