Correlation of PaCO2 to the Inspired and Expired Oxygen Gradient

Completed

• Conditions: Neurosurgery

• Registration Number: NCT01513213
• Lead Sponsor: Swedish Medical Center

Brief Summary

The purpose of this study is to evaluate whether a correlation exists between the partial pressure of carbon dioxide existing within arterial blood and the gradient between inhaled and exhaled fractions of oxygen.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-10
• Study First Submitted: 2012-01-05
• Study First Submitted QC: 2012-01-16
• Study First Posted: 2012-01-20
• Primary Completion: 2014-05
• Study Completion: 2016-12
• Status Verified: 2017-01
• Last Update Submitted: 2017-01-20
• Last Update Posted: 2017-01-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 65

Inclusion Criteria

• Age 18 to 65.
• Scheduled for surgical procedure that will last at least 2 hours.
• Arterial cannulation is planned because of either the complexity of the surgery or patient comorbidity.
• At least two arterial blood gas analyses are planned during the surgery.

Exclusion Criteria

• No arterial cannulation is necessary or planned for the procedure.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Correlate the level of carbon dioxide within arterial blood to inspired and expired oxygen gradient.	At least 2 hours	Compare the levels of carbon dioxide found in the patient's blood to the amounts of carbon dioxide and oxygen in the air that the patient inhales and exhales. If a relationship exists between the levels of carbon dioxide in the blood and the levels of carbon dioxide and oxygen inhaled and exhaled by the patient, anesthesiologists will be able to use this relationship to adjust ventilators during anesthesia without having to take blood from an artery.

Trial Locations

Locations (1)

Swedish Medical Center; 🇺🇸 Seattle, Washington, United States