NCT00660465Unknown不适用
Exploring the Relationship Between Varying CO2 Levels and the Regional BOLD Signal, by Using Breathing Exercises .
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 6
- 试验地点
- 1
研究概览
简要总结
The purpose of this study is to explore how arterial PaCO2 effect regional Blood Oxygen Level Dependent (BOLD) signal, and indirectly the brain regional O2 level .
详细描述
Among many parameters effecting cerebral blood flow(CBF), partial pressure of CO2 (PaCO2) in arterial blood has a significant effect. A small increase in arterial PaCO2 level will cause a significant increase of CBF , followed by increase of O2 level . The main objective is to explore the effect of arterial PaCO2 level on regional CBF and brain O2 level, by using breathing exercises to modulate arterial PaCO2. The regional Blood Oxygen Level Dependent (BOLD) signal produced by MRI , will indicate the regional O2 level.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •adults over 18 years old .
排除标准
- •under 18 years old.
- •Artificial pacemaker
- •implantable cardioverter-defibrillator (ICD)
- •Hearing aid, implantable or portable.
- •artificial heart valve
- •Surgical clips
- •Metal fragments in eyes
- •Electronic stimulators
- •Implanted pumps
- •Implantable Neurostimulation Device
- •metal fragments of any sort
- •Permanent makeup or tattoo
- •transfusion pump
- •pregnant or breast feeding women
- •False teeth , retainer or dental crown
研究者
研究点 (1)
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