Development of the Partial Pressure of Carbon Dioxide During Exercise and at Night in Patients With Chronic Obstructive Pulmonary Disease (COPD) IV
Not Applicable
Completed
- Conditions
- Chronic Obstructive Pulmonary Disease
- Interventions
- Procedure: 6-minute walking test
- Registration Number
- NCT01696916
- Lead Sponsor
- Schön Klinik Berchtesgadener Land
- Brief Summary
The aim of this study is to investigate the development of partial pressure of carbon dioxide during the 6-min walking test and during night in Chronic Obstructive Pulmonary Disease (COPD)-patients (GOLD stage IV). Therefore the partial pressure of carbon dioxide, oxygen saturation and the heart rate are registered by a device called "Sentec" during the mentioned periods. In addition a measurement of activity is realised by an activity monitor ("Sensewear").
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 75
Inclusion Criteria
- COPD IV with and without a respiratory insufficiency
- maximal paCO² of 55mmHg at admission (taken at rest by blood gas analysis without LTOT)
Exclusion Criteria
- paCO² > 55mmHg
- non-invasive ventilation
- acute exacerbation
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description exercise testing 6-minute walking test 6-minute walking test with pCO2 and pO2 measurement
- Primary Outcome Measures
Name Time Method Increase of PaCO2 more than 5mmHg From time of starting 6-minute walking test until the time of PaCO2-increase of more than 5mmHg assessed up to 6 minutes.
- Secondary Outcome Measures
Name Time Method Change of PaCO2 From the beginning of the 6-minute walking test until peak PaCO2, assessed up to 6 minutes
Trial Locations
- Locations (1)
Klinikum Berchtesgadener Land
🇩🇪Berchtesgaden, Germany