临床试验/NCT01696916

NCT01696916已完成不适用

Development of the Partial Pressure of Carbon Dioxide During 6-min Walking Test and at Night in Patients With Chronic Obstructive Pulmonary Disease IV

Schön Klinik Berchtesgadener Land1 个研究点分布在 1 个国家目标入组 75 人开始时间: 2012年3月最近更新: 2014年4月15日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方: Schön Klinik Berchtesgadener Land
入组人数: 75
试验地点: 1
主要终点: Increase of PaCO2 more than 5mmHg

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

The aim of this study is to investigate the development of partial pressure of carbon dioxide during the 6-min walking test and during night in Chronic Obstructive Pulmonary Disease (COPD)-patients (GOLD stage IV). Therefore the partial pressure of carbon dioxide, oxygen saturation and the heart rate are registered by a device called "Sentec" during the mentioned periods. In addition a measurement of activity is realised by an activity monitor ("Sensewear").

研究设计

研究类型: Interventional
分配方式: Na
干预模型: Single Group
主要目的: Basic Science
盲法: None

入排标准

年龄范围: 30 Years 至 75 Years（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•COPD IV with and without a respiratory insufficiency
•maximal paCO² of 55mmHg at admission (taken at rest by blood gas analysis without LTOT)

排除标准

•paCO² > 55mmHg
•non-invasive ventilation
•acute exacerbation

结局指标

主要结局

Increase of PaCO2 more than 5mmHg

时间窗: From time of starting 6-minute walking test until the time of PaCO2-increase of more than 5mmHg assessed up to 6 minutes.

次要结局

Change of PaCO2(From the beginning of the 6-minute walking test until peak PaCO2, assessed up to 6 minutes)

研究者

发起方

Schön Klinik Berchtesgadener Land

申办方类型

Other

责任方

Principal Investigator

主要研究者

Klaus Kenn

Head physician (department of pneumology)

Schön Klinik Berchtesgadener Land

研究点 (1)

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