Airway Disease Analysis and Preventio

• Conditions: Allergic rhinitisAsthmaChronic rhinosinusitis; J30; J45; J32; Vasomotor and allergic rhinitis; Asthma; Chronic sinusitis

• Registration Number: DRKS00023381
• Lead Sponsor: Klinikum rechts der Isar der Technischen Universität München

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-10-27
• Study Completion: 2021-12-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 570

Inclusion Criteria

1. Individuals in good health otherwise from respiratory disease
2. Patients suffering from at least two symptoms that suggest Respiratory Inflammatory Disease:
- Recurrent Sneeze
- Itchy Eyes
- Anterior or posterior rhinorrhea
- Blocked Nose
- Cough
- Wheeze or Asthma attacks
- Seasonal variation of airway symptoms
3. Age between 18 and 75 years

Exclusion Criteria

1. Inability to understand or to communicate with investigator or to understand the aim of the study
2. Any currently relevant medical history of addiction to alcohol, drugs or medical substances
3. Any currently relevant medical history of clinically significant internal
disease that is not primarily affecting the airways and that is not
controlled by medication
4. Concommitant medication: Intake of topical nasal steroids, systemic leukotriene antagonists or any antihistamines within the last 7 days before study visit or systemic glucocorticoids within the last 10 days or Specific Immunotherapy within the last 5 years
5. Pregnancy

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To assess sensitivity and specificity of biomarkers in local airway secretions in<br>comparison to serum expression.

Secondary Outcome Measures

Name	Time	Method
To assess tolerability of sampling methods.